News
15/12 – Hervé Rigneault : Multiphoton imaging endoscopy
Tuesday, 15 Dec 2020, 10h30 – Zoom webinar – Ask link to a SPPIN member. Hervé Rigneault – Institut Fresnel, Marseille In this talk I will present our recent advances to build flexible probes that are able to perform 2-photon ...
Heating, not highly non-linear photo damage is limiting for 920-nm 2-imaging
Unraveling how neural networks process and represent sensory information and how these cellular signals instruct behavioral output is a main goal in neuroscience. Two-photon activation of optogenetic actuators and calcium (Ca 2+) imaging with gen ...
Open Post-doctoral position at the Saints-Pères Paris Institute for Neurosciences (Université de Paris)
OPEN POSTDOC Development of a compressed wavefront sensor with a thin scattering Hartmann-mask We offer a 15-month postdoc position (renewable 15 months) starting on January 2021, funded by the french national agency (ANR) for developing a compr ...
Open PhD position at the Saints-Pères Paris Institute for Neurosciences (Université de Paris)
OPEN PHD in Zytnicki lab Title: “Restoration of excitation/inhibition balance to modulate motor neuron degeneration in Amyotrophic Lateral Sclerosis (ALS)“ A PhD position, under the supervision of Daniel Zytnicki, is available in the ...
Internship offer 2020-2021 for master project : “Immunolabelling of cleared thick three-dimensional brain sections”
INTERNSHIP OFFER, Oheim lab, academic year 2020-21 MASTER PROJECT: Immunolabelling of cleared thick three-dimensional brain sections Fluorescent-protein expression in genetically identified cell populations, along with advances in tissue clearing [Con15, R ...
Internship offer 2020-2021 for master project : “Labelling of active astrocytes with genetically encoded Calcium integrators – an in vitro proof-of-concept study.”
INTERNSHIP OFFER, Oheim lab, academic year 2020-21 MASTER PROJECT: Labelling of active astrocytes with genetically encoded Calcium integrators – an in vitro proof-of-concept study. About half of the cells in the human brain are not neurons. Our aim is to ...
Spectral correlations in forward scattering media
Artist illustration of chromatic speckle expansion after a scattering sample. (© Clément Molinier) Imaging deep in scattering tissues has been typically achieved by exciting non-linear optical processes thanks to broadband ultrashort laser pulses. Scatte ...
The SPPIN supports Paris Hospitals in times of Corona
Together with other laboratories of the Saints Pères Biomedical Sciences Site (Campus Saint Germain) the SPPIN has collected consumables and lab material in support of the Necker, Cochin Hospitals on the left bank and Bichat, Lariboisière, Baujon Hospita ...
STANISLAS PhD project selected by CNRS and U. Toronto
The CNRS and the University of Toronto selected a joint PhD-and research grant involving SPPIN’s team 1 (Oheim) and the laboratory of Molecular Biophysics at the Department of Biochemistry (Yip) at U Toronto. In the framework of this 3-year research coll ...
Evanescence in emission: seeing fluorescence from supercritical angles
Read it here : Supercritical angle microscopy and spectroscopy Authors: Martin Oheim, Adi Salomon, Maia Brunstein Abstract: Fluorescence detection, either involving propagating or near-field emission, is widely being used in spectroscopy, sensing and micro ...
Next seminars
Coming soon...
Fresh from the press
Articles
- Rapid Motor Adaptation via Population-level Modulation of Cerebellar Error Signals
Vinh Nguyen, Brandon M Stell : (preprint), in press - Associative plasticity of granule cell inputs to cerebellar Purkinje cells
Rossella Conti, Céline Auger : (preprint), in press - Unveiling the Phenotypic Variability of Macrophages: Insights from Donor Diversity and Pooling Strategies.
Taciak B, Grochowska A, Górczak M, Górka E, Skorzynski M, Białasek M, Rygiel TP, Król M : Int J Mol Sci, 2025 - Harnessing macrophage-drug conjugates for allogeneic cell-based therapy of solid tumors via the TRAIN mechanism.
Taciak B, Bialasek M, Kubiak M, Marszalek I, Gorczak M, Osadchuk O, Kurpiel D, Strzemecki D, Barwik K, Skorzynski M, Nowakowska J, Lipiński W, Kiraga Ł, Brancewicz J, Klopfleisch R, Krzemiński Ł, Gorka E, Smolarska A, Padzinska-Pruszynska I, Siemińska M, Guzek J, Kutner J, Kisiala M, Wozniak K, Parisi G, Piacentini R, Cassetta L, Forrester LM, Bodnar L, Weiss T, Boffi A, Kucharzewska P, Rygiel TP, Krol M : Nat Commun, 2025 - A first morphological and electrophysiological characterization of Fañanas cells of the mouse cerebellum.
Singer A, Trigo F, Vinel L, Gruere O, Llano I, Oheim M : J Physiol, 2025 - Imaging the enteric nervous system
Doriane Hazart, Marwa Moulzir, Brigitte Delhomme, Martin Oheim, Clément Ricard : Frontiers in Neuroanatomy (accepted), 2025 - Fast tissue clearing and volume imaging techniques for anatomy
Clément Ricard, Doriane Hazart, Brigitte Delhomme, Marwa Moulzir, Irina Rakotoson, Martin Oheim : Microscopy Research & Technique (accepted), 2025 - Managing Surface Energy Dynamics for Enhanced Axonal Growth: An Overview of present and Future Challenges
Océane Sénépart, Claire Legay, Ahmed Hamraoui : Biophysics Reviews, 2025 - Complementary Speckle Stimulated Emission Depletion Microscopy
Payvand Arjmand, Samlan Chandran Thodika, Elsa Bivas, Haoyang Li, Martin Oheim, Hiroyuki Yoshida, Etienne Brasselet, Marc Guillon : ACS Photonics, 2025 - Ice templating water-stable macroporous polysaccharide hydrogels to mimic plant stems.
Komiyama K, Allard M, Eschenbrenner C, Sicard C, Hamraoui A, Fernandes F : Journal of Materials Chemistry B, 2025 - Breast Cancer Plasticity after Chemotherapy Highlights the Need for Re-Evaluation of Subtyping in Residual Cancer and Metastatic Tissues.
Padzińska-Pruszyńska IB, Akbar MW, Isbilen M, Górka E, Kucukkaraduman B, Canlı SD, Dedeoğlu E, Azizolli S, Cela I, Akcay AG, Hakanoglu H, Bodnar L, Cierniak S, Kozielec Z, Pruszyński JJ, Bittel M, Gure AO, Król M, Taciak B : Int J Mol Sci, 2024 - The Molecules Lost New Compounds Binding at the Histamine Site of the NMDA Receptor (NMDA(HA)R).
Armand V : Adv Neur Neur Sci, 2024 - Histamine H1-receptor-mediated modulation of NMDA receptors signaling responses
J-M Arrang, V Armand : Pharmacol Res Perspect, 2024 - Brain inflammation and cognitive decline induced by spinal cord injury can be reversed by spinal cord cell transplants
Q Delarue, A Robac, F Semprez, C Duclos, B Pileyre, P Neveu, C Raimond, G Riou, I Ziane, N Guérout : Brain Behav Immun, 2024 - Spinal microcircuits go through multiphasic homeostatic compensations in a mouse model of motoneuron degeneration.
Nascimento F, Özyurt MG, Halablab K, Bhumbra GS, Caron G, Bączyk M, Zytnicki D, Manuel M, Roselli F, Brownstone R, Beato M : Cell Rep, 2024 - Contributions of Surface and Interface Physical Chemistry to Biology
Ahmed Hamraoui : (preprint), 2024 - Hyperspectral wavefront sensing with a multicore fiber
Baptiste Blochet, Nathalie Lebas, Pascal Berto, Dimitrios Papadopoulos, Marc Guillon : (under review at Nat Commun), 2024 - A Polarimetric Wavefront Imager
Baptiste Blochet, Grégoire Lelu, Miguel A Alonso, Marc Guillon : (under review at Optica), 2024 - Projection-specific integration of convergent thalamic and retrosplenial signals in the presubicular head direction cortex
Louis Richevaux, Dongkyun Lim, Mérie Nassar, Léa Dias Rodrigues, Constanze Mauthe, Ivan Cohen, Nathalie Sol-Foulon, Desdemona Fricker : (preprint), 2024 - Presubicular VIP expressing interneurons receive facilitating excitation from anterior thalamus.
Nassar M, Richevaux L, Lim D, Tayupo D, Martin E, Fricker D : Neuroscience, 2024 - Involvement of kinases in memory consolidation of inhibitory avoidance training.
Montiel I, Bello-Medina PC, Prado-Alcalá RA, Quirarte GL, Verdín-Ruvalcaba LA, Marín-Juárez TA, Medina AC : Rev Neurosci, 2024 - Elucidating the Activation Mechanism of the Proton-sensing GPR68 Receptor.
Matsingos C, Howell LA, McCormick PJ, Fornili A : J Mol Biol, 2024 - The gut, a whistleblower, in the early stages of Parkinson’s disease
Doriane Hazart, Malvyne Rolli-Derkinderen, Brigitte Delhomme, Pascal Derkinderen, Martin Oheim, Clément Ricard : Médecine/sciences, 2024 - Characterizing human astrocyte calcium signaling in a cerebral organoid
Kaitlin Szederkenyi, Liliana Attisano, Martin Oheim, Christopher M Yip : Biophys J, 2024 - L’intestin, lanceur d’alerte, dans les prémices de la maladie de Parkinson
Doriane Hazart, Malvyne Rolli-Derkinderen, Brigitte Delhomme, Pascal Derkinderen, Martin Oheim, Clément Ricard : Médecine/sciences, 2024 - Lesion-induced impairment of therapeutic capacities of olfactory ensheathing cells in an autologous transplantation model for treatment of spinal cord injury
Quentin Delarue, Matthis Brodier, Pauline Neveu, Laurine Moncomble, Alizée Hugede, Axelle Blondin, Amandine Robac, Clémence Raimond, Pamela Lecras, Gaëtan Riou, Nicolas Guérout : (preprint), 2024 - Complementarity between Brillouin signature and Scholte wave for controlled elasticity in fibrillated collagen medium for culture cell
Ahmed Hamraoui, Océane Sénépart, Laurent Belliard : Applied Physics Letters, 2024 - MFSD1 with its accessory subunit GLMP functions as a general dipeptide uniporter in lysosomes
Katharina Esther Julia Jungnickel, Océane Guelle, Miharu Iguchi, Wentao Dong, Vadim Kotov, Florian Gabriel, Cécile Debacker, Julien Dairou, Isabelle McCort-Tranchepain, Nouf N Laqtom, Sze Ham Chan, Akika Ejima, Kenji Sato, David Massa López, Paul Saftig, Ahmad Reza Mehdipour, Monther Abu-Remaileh, Bruno Gasnier, Christian Löw, Markus Damm : Nature Cell Biology, 2024 - Novel Inhibitory Site Revealed by XAP044 Mode of Action on the Metabotropic Glutamate 7 Receptor Venus Flytrap Domain.
Cristiano N, Cabayé A, Brabet I, Glatthar R, Tora A, Goudet C, Bertrand HO, Goupil-Lamy A, Flor PJ, Pin JP, McCort-Tranchepain I, Acher FC : J Med Chem, 2024 - Epitope Identification of an mGlu5 Receptor Nanobody Using Physics-Based Molecular Modeling and Deep Learning Techniques.
Eshak F, Pion L, Scholler P, Nevoltris D, Chames P, Rondard P, Pin JP, Acher FC, Goupil-Lamy A : J Chem Inf Model, 2024 - CBX3 antagonizes IFNγ/STAT1/PD-L1 axis to modulate colon inflammation and CRC chemosensitivity.
Xiang Y, Mata-Garrido J, Fu Y, Desterke C, Batsché E, Hamaï A, Sedlik C, Sereme Y, Skurnik D, Jalil A, Onifarasoaniaina R, Frapy E, Beche JC, Alao R, Piaggio E, Arbibe L, Chang Y : EMBO Mol Med, 2024 - Single-shot digital optical fluorescence phase conjugation through forward multiple-scattering samples
TENGFEI WU, YIXUAN ZHANG, BAPTISTE BLOCHET, PAYVAND ARJMAND, PASCAL BERTO, AND MARC GUILLON : Science advances, 2024 - Multiplexed wavefront sensing with a thin diffuser
Tengfei Wu, Marc Guillon, Gilles Tessier, and Pascal Berto : Optica, 2024 - Design, Synthesis, Pharmacology, and In Silico Studies of (1S,2S,3S)-2-((S)-Amino(carboxy)methyl)-3-(carboxymethyl)cyclopropane-1-carboxylic Acid (LBG30300): A Picomolar Potency Subtype-Selective mGlu(2) Receptor Agonist.
Liu N, Eshak F, Malhaire F, Brabet I, Prézeau L, Renard E, Pin JP, Acher FC, Staudt M, Bunch L : J Med Chem, 2024 - A maximum of two readily releasable vesicles per docking site at a cerebellar single active zone synapse.
Silva M, Tran V, Marty A : Elife, 2024 - A colour-encoded nanometric ruler for axial super-resolution microscopies
Ilya Olevsko, Omer Shavit, Moshe Feldberg, Yossi Abulafia, Adi Salomon, Martin Oheim : Optics Communications, 2024