News
MITACS GLOBALLINK fellowship for work on polarisation effects in confocal evanescent (TIR-SAF) super-resolution microscopies applied to cell adhesion
We congratulate Kaitlin Szederkenyi, a master student in Applied Science and Biomedical Engineering from the University of Toronto to her MITACS fellowship. Kaitlin will join team 1 of the SPPIN for a 4-month internship. She will be working with Martin Oh ...
How to calibrate evanescent-wave penetration depths for biological TIRF microscopy?
Total internal reflection sets up an evanescent wave that – when used for microscopic imaging – renders the microscope short-sighted and enables the selective observation of the near-membrane space. But how deep is deep? In this Biophysical Pe ...
Fast volumetric Imaging of Brain Organoids With a New Single-Objective Planar-Illumination Two-Photon Microscope
Imaging large tissue volumes at high spatio-temporel resolution has been a major challenge for scanning-type 2-photon microscopes. Now, SPPIN researchers around Martin Oheim and from TILL.id (Munich) designed and successfully validated a new microscope sch ...
Chateaubriand fellowship awarded for work on OASIS microscope
Last academic year’s SPPIN-Paris Descartes’ invited Professor Adi Salomon (link to: www.lab-salomon.com) was awarded a Chateaubriand Senior Fellowship by the French Embassy in Israel. Salomon and some of her collaborators will come to work on the OASIS ...
Call for contributions to Special Issue of Microscopy Research and Technique (Wiley) on Photobleaching and Photodamage
Medically efficient treatments often go along with unwanted side effects. In much the same manner, microscopic imaging at high spatio-temporal resolution pushes the limits by destroying fluorescent labels, affecting the biological process under study or ev ...
ERASMUS+ fellowship for work on histaminergic NMDA-receptor modulation
We congratulate Mona Kappes, a med student from Erlangen-Nürnberg University who took the 2017 Olang Summer school on how new genetic and imaging techniques allow to address the complexity of the brain (Oheim/Kirchoff), to the ERASMUS+ fellowship she won ...
2nd Eureka! EUROSTARS grant awarded to SPPIN researchers
After the successful OASIS project (www.biorxiv.org/content/early/2018/11/03/461335 , www.till-id.com/en/idea_projects_OASIS.php) a second EUROSTARS grant has been awarded to the SPPIN. A team of researchers around Martin Oheim, head of the Biophysics of N ...
Two teams from the SPPIN awarded ANR grant
Brandon Stell and Céline Auger, from the team Cerebellar Neurophysiology, along with Marin Manuel, from the team Motor Neurons & NeuroMuscular Junctions, both part of the SPPIN, have been awarded an ANR grant for their project on “Integration of spi ...
Seana O’regan and Alain Marty received the CNRS medal of honour
On Wednesday, July 10, 2019, Seana O’REGAN and Alain MARTY were awarded the CNRS Medal of Honor for their participation in the organization’s outreach and research activity and the quality of their services to science. ...
The “Institut Universitaire de France” supports “singular microscopy”
Comparison of regular 3D point scanning microscopy (a) with super-resolution compressed sensing microscopy with speckle patterns (b). Super-resolution was achieved here by saturating fluorescence excitation. (From M. Pascucci et al., Nat. Comm. 2019). Cong ...
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Fresh from the press
Articles
- Rapid Motor Adaptation via Population-level Modulation of Cerebellar Error Signals
Vinh Nguyen, Brandon M Stell : (preprint), in press - Associative plasticity of granule cell inputs to cerebellar Purkinje cells
Rossella Conti, Céline Auger : (preprint), in press - Elucidating the Activation Mechanism of the Proton-sensing GPR68 Receptor.
Matsingos C, Howell LA, McCormick PJ, Fornili A : J Mol Biol, 2024 - The gut, a whistleblower, in the early stages of Parkinson’s disease
Doriane Hazart, Malvyne Rolli-Derkinderen, Brigitte Delhomme, Pascal Derkinderen, Martin Oheim, Clément Ricard : Médecine/sciences, 2024 - Characterizing human astrocyte calcium signaling in a cerebral organoid
Kaitlin Szederkenyi, Liliana Attisano, Martin Oheim, Christopher M Yip : Biophys J, 2024 - L’intestin, lanceur d’alerte, dans les prémices de la maladie de Parkinson
Doriane Hazart, Malvyne Rolli-Derkinderen, Brigitte Delhomme, Pascal Derkinderen, Martin Oheim, Clément Ricard : Médecine/sciences, 2024 - Complementary Speckle STED Microscopy
Payvand Arjmand, Samlan Chandran Thodika, Elsa Bivas, Haoyang Li, Martin Oheim, Hiroyuki Yoshida, Etienne Brasselet, Marc Guillon : (preprint), 2024 - Lesion-induced impairment of therapeutic capacities of olfactory ensheathing cells in an autologous transplantation model for treatment of spinal cord injury
Quentin Delarue, Matthis Brodier, Pauline Neveu, Laurine Moncomble, Alizée Hugede, Axelle Blondin, Amandine Robac, Clémence Raimond, Pamela Lecras, Gaëtan Riou, Nicolas Guérout : (preprint), 2024 - Complementarity between Brillouin signature and Scholte wave for controlled elasticity in fibrillated collagen medium for culture cell
Ahmed Hamraoui, Océane Sénépart, Laurent Belliard : Applied Physics Letters, 2024 - MFSD1 with its accessory subunit GLMP functions as a general dipeptide uniporter in lysosomes
Katharina Esther Julia Jungnickel, Océane Guelle, Miharu Iguchi, Wentao Dong, Vadim Kotov, Florian Gabriel, Cécile Debacker, Julien Dairou, Isabelle McCort-Tranchepain, Nouf N Laqtom, Sze Ham Chan, Akika Ejima, Kenji Sato, David Massa López, Paul Saftig, Ahmad Reza Mehdipour, Monther Abu-Remaileh, Bruno Gasnier, Christian Löw, Markus Damm : Nature Cell Biology, 2024 - Novel Inhibitory Site Revealed by XAP044 Mode of Action on the Metabotropic Glutamate 7 Receptor Venus Flytrap Domain.
Cristiano N, Cabayé A, Brabet I, Glatthar R, Tora A, Goudet C, Bertrand HO, Goupil-Lamy A, Flor PJ, Pin JP, McCort-Tranchepain I, Acher FC : J Med Chem, 2024 - Epitope Identification of an mGlu5 Receptor Nanobody Using Physics-Based Molecular Modeling and Deep Learning Techniques.
Eshak F, Pion L, Scholler P, Nevoltris D, Chames P, Rondard P, Pin JP, Acher FC, Goupil-Lamy A : J Chem Inf Model, 2024 - Ice templating water-stable macroporous polysaccharide hydrogels to mimic plant stems.
Komiyama K, Allard M, Eschenbrenner C, Sicard C, Hamraoui A, Fernandes F : (preprint), 2024 - CBX3 antagonizes IFNγ/STAT1/PD-L1 axis to modulate colon inflammation and CRC chemosensitivity.
Xiang Y, Mata-Garrido J, Fu Y, Desterke C, Batsché E, Hamaï A, Sedlik C, Sereme Y, Skurnik D, Jalil A, Onifarasoaniaina R, Frapy E, Beche JC, Alao R, Piaggio E, Arbibe L, Chang Y : EMBO Mol Med, 2024 - Single-shot digital optical fluorescence phase conjugation through forward multiple-scattering samples
TENGFEI WU, YIXUAN ZHANG, BAPTISTE BLOCHET, PAYVAND ARJMAND, PASCAL BERTO, AND MARC GUILLON : Science advances, 2024 - Multiplexed wavefront sensing with a thin diffuser
Tengfei Wu, Marc Guillon, Gilles Tessier, and Pascal Berto : Optica, 2024 - Design, Synthesis, Pharmacology, and In Silico Studies of (1S,2S,3S)-2-((S)-Amino(carboxy)methyl)-3-(carboxymethyl)cyclopropane-1-carboxylic Acid (LBG30300): A Picomolar Potency Subtype-Selective mGlu(2) Receptor Agonist.
Liu N, Eshak F, Malhaire F, Brabet I, Prézeau L, Renard E, Pin JP, Acher FC, Staudt M, Bunch L : J Med Chem, 2024 - A maximum of two readily releasable vesicles per docking site at a cerebellar single active zone synapse.
Silva M, Tran V, Marty A : Elife, 2024 - A colour-encoded nanometric ruler for axial super-resolution microscopies
Ilya Olevsko, Omer Shavit, Moshe Feldberg, Yossi Abulafia, Adi Salomon, Martin Oheim : Optics Communications, 2024 - Morphological Heterogeneity of Astrocytes in a Cerebral Organoid
K Szederkenyi, L Attisano, M Oheim, CM Yip : Glia, 2023 - Methods and applications in frontiers in neuroanatomy
Clément Ricard, Lidia Alonso-Nanclares, Basilis Zikopoulos, Martin Oheim : Front Neuroanat, 2023 - The collagen ColQ binds to LRP4 and regulates the activation of the Muscle-Specific Kinase–LRP4 receptor complex by agrin at the neuromuscular junction
Thi Minh Uyen Dao, Susie Barbeau, Julien Messéant, Bruno Della-Gaspera, Tahar Bouceba, Fannie Semprez, Claire Legay, and Alexandre Dobbertin : J Biol Chem, 2023 - Advances in Spinal Cord Neuromodulation: The Integration of Neuroengineering, Computational Approaches, and Innovative Conceptual Frameworks.
Pradat PF, Hayon D, Blancho S, Neveu P, Khamaysa M, Guerout N : J Pers Med, 2023 - Mesenchymal calcium waves underpin intestinal smooth muscle differentiation
Chevalier N R, Zig L, Gomis A, Amedzrovi Agbesi R, Pontoizeau L, Eude-Le Parco I, Rouach N, Arnoux I, De Santa Barbara P, Faure S : Communications Biology, 2023 - Electrical and Mechanosensitive Activity of the Mouse Fetal Enteric Nervous System
Amedzrovi Agbesi R, Spencer N, Hebberd T, Chevalier N R : J Physiol, 2023 - Multisensory gaze stabilization in response to subchronic alteration of vestibular type I hair cells.
Schenberg L, Palou A, Simon F, Bonnard T, Barton CE, Fricker D, Tagliabue M, Llorens J, Beraneck M : Elife, 2023 - Beneficial Effect of Bee Venom and Its Major Components on Facial Nerve Injury Induced in Mice.
Er-Rouassi H, Bakour M, Touzani S, Vilas-Boas M, Falcão S, Vidal C, Lyoussi B : Biomolecules, 2023 - PTBP1 regulates injury responses and sensory pathways in adult peripheral neurons.
Alber S, Di Matteo P, Zdradzinski MD, Dalla Costa I, Medzihradszky KF, Kawaguchi R, Di Pizio A, Freund P, Panayotis N, Marvaldi L, Doron-Mandel E, Okladnikov N, Rishal I, Nevo R, Coppola G, Lee SJ, Sahoo PK, Burlingame AL, Twiss JL, Fainzilber M : Sci Adv, 2023 - Depolarization-induced bursts of miniature synaptic currents in individual synapses of developing cerebellum.
Le Guellec B, Gomez LC, Malagon G, Collin T, Marty A : J Gen Physiol, 2023 - Prioritized docking of synaptic vesicles provided by a rapid recycling pathway
Tran V, Silva M, Marty A : IScience, 2023 - Bumetanide increases postsynaptic inhibition after chronic SCI and decreases presynaptic inhibition with step-training.
Caron G, Bilchak J, Côté MP : J Physiol, 2023 - KCa1.1 channels contribute to optogenetically driven post-stimulation silencing in cerebellar molecular layer interneurons.
Kassa M, Bradley J, Jalil A, Llano I : J Gen Physiol, 2023 - Characterizing nanometric thin films with far-field light
Klimovsky H, Shavit O, Julien C, Olevsko I, Hamode M, Abulafia Y, Suaudeau H, Armand V, Oheim M, Salomon A : Adv Opt Mater, 2023