News
10 June 2025 – Stephanie RUDOLPH – A Mechanism for Amplifying Sparse Neuromodulatory Signals in Electrically Coupled Interneuron Networks
Prof Stephanie RUDOLPH, Albert Einstein College of Medicine, New York SPPIN’s webinar 2025, 10 June at 11h, SPPIN common room, 3rd floor A Mechanism for Amplifying Sparse Neuromodulatory Signals in Electrically Coupled Interneuron Networks ...
20 Mai 2025 – Alexandra FRAGOLA – Fast adaptive optics light-sheet microscopy for in vivo high-resolution imaging at depth
Prof Alexandra FRAGOLA, ISMO, Université Paris Saclay (Orsay) SPPIN’s webinar 2024, 20 May at 11h, SPPIN common room, 3rd floor Fast adaptive optics light-sheet microscopy for in vivo high-resolution imaging at depth The study of fast biolo ...
The Association Française du Syndrome de Rett supports Nicolas PANAYOTIS
Congratulations to Nicolas PANAYOTIS (Team 7) who was awarded a 3-years Research Grant by the French Rett Syndrome Patient Advocacy Organization “Association Française du Syndrome de Rett” (or AFSR). Funded project: NewMOTORS ‘Development ...
SPPIN’s Floriane Eshak receives distinguished thesis award for advancing psychiatric treatment
Floriane Eshak, who conducted her doctoral research at SPPIN laboratory last year, has been awarded a prestigious 2024 Solemn Thesis Prize from the Chancellerie des universités de Paris. Under the supervision of Francine Acher (SPPIN team 6) and Anne Gou ...
Brandon Stell and Boris Barbour’s PubPeer Wins the 200.000€’s Einstein Award
The Einstein Foundation has awarded its prestigious 2024 Institutional Award to PubPeer, the post-publication peer review platform co-founded by SPPIN’s Brandon Stell and IBENS’s Boris Barbour. The foundation award, in collaboration with th ...
2 Open PhD and 14 Master projects
SPPIN is recruiting ! 14 open Master projects Here are the titles : Team 1 – Biophysics of the brain : Imaging the dissipation of Ca2+ micro domains w/ SAF BFP imaging A reproducible metric for tissue clearing with quantitative phase ...
The SPPIN proudly hosted the kick-off meeting of the CNRS IRN “OMNI-TOOLS” international research network
Experimental neuroscience, as we know it today, is largely building on techniques that were originally developed in very diverse communities including non-linear optics, photochemistry, or light-shaping techniques. What if we bring together leading act ...
24th september 2024 – Pablo BLINDER – The circuit basis of stereo vision
Prof Pablo BLINDER, Neurobiology, Biochemistry and Biophysics School,George S. Wise Faculty of Life Sciences, and Sagol School for Neuroscience, Tel Aviv University SPPIN’s webinar 2024, 5 June at 10h30, R229 (after the progress report) Exploring ...
Appel à communication du “12h30 de la recherche”
Nous relayons cet appel important de Diana Zala (de l’IPNP) et Nicolas Panayotis (chef de l’équipe n°7 du SPPIN) : ...
Congrats to Daniel Zytnicki for the CNRS Medal of Honor!
The text in cuneiform script is an extract from the beginning of the epic of Gilgamesh in its Neo-Assyrian version, 7th century BC: “He who has seen all, he has contemplated what was secret and discovered what was hidden” (source). On June 1 ...
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Fresh from the press
Articles
- Rapid Motor Adaptation via Population-level Modulation of Cerebellar Error Signals
Vinh Nguyen, Brandon M Stell : (preprint), in press - Associative plasticity of granule cell inputs to cerebellar Purkinje cells
Rossella Conti, Céline Auger : (preprint), in press - Combinatorial Sample-and Back-Focal-Plane (BFP) Imaging. Pt. I: Instrument and acquisition parameters affecting BFP images and their analysis
Omer Shavit, Hervé Suaudeau, Carine Julien, Hodaya Klimovsky, Natalia Mañas-Chavernas, Adi Salomon, Martin Oheim : (preprint), 2025 - Managing surface energy dynamics for enhanced axonal growth: An overview of present and future challenges
Sénépart O, Legay C, Hamraoui A : Biophysics Reviews, 2025 - Unveiling the Phenotypic Variability of Macrophages: Insights from Donor Diversity and Pooling Strategies.
Taciak B, Grochowska A, Górczak M, Górka E, Skorzynski M, Białasek M, Rygiel TP, Król M : Int J Mol Sci, 2025 - Harnessing macrophage-drug conjugates for allogeneic cell-based therapy of solid tumors via the TRAIN mechanism.
Taciak B, Bialasek M, Kubiak M, Marszalek I, Gorczak M, Osadchuk O, Kurpiel D, Strzemecki D, Barwik K, Skorzynski M, Nowakowska J, Lipiński W, Kiraga Ł, Brancewicz J, Klopfleisch R, Krzemiński Ł, Gorka E, Smolarska A, Padzinska-Pruszynska I, Siemińska M, Guzek J, Kutner J, Kisiala M, Wozniak K, Parisi G, Piacentini R, Cassetta L, Forrester LM, Bodnar L, Weiss T, Boffi A, Kucharzewska P, Rygiel TP, Krol M : Nat Commun, 2025 - A first morphological and electrophysiological characterization of Fañanas cells of the mouse cerebellum.
Singer A, Trigo F, Vinel L, Gruere O, Llano I, Oheim M : J Physiol, 2025 - Imaging the enteric nervous system
Doriane Hazart, Marwa Moulzir, Brigitte Delhomme, Martin Oheim, Clément Ricard : Frontiers in Neuroanatomy (accepted), 2025 - Fast tissue clearing and volume imaging techniques for anatomy
Clément Ricard, Doriane Hazart, Brigitte Delhomme, Marwa Moulzir, Irina Rakotoson, Martin Oheim : Microscopy Research & Technique (accepted), 2025 - Complementary Speckle Stimulated Emission Depletion Microscopy
Payvand Arjmand, Samlan Chandran Thodika, Elsa Bivas, Haoyang Li, Martin Oheim, Hiroyuki Yoshida, Etienne Brasselet, Marc Guillon : ACS Photonics, 2025 - Ice templating water-stable macroporous polysaccharide hydrogels to mimic plant stems.
Komiyama K, Allard M, Eschenbrenner C, Sicard C, Hamraoui A, Fernandes F : Journal of Materials Chemistry B, 2025 - Breast Cancer Plasticity after Chemotherapy Highlights the Need for Re-Evaluation of Subtyping in Residual Cancer and Metastatic Tissues.
Padzińska-Pruszyńska IB, Akbar MW, Isbilen M, Górka E, Kucukkaraduman B, Canlı SD, Dedeoğlu E, Azizolli S, Cela I, Akcay AG, Hakanoglu H, Bodnar L, Cierniak S, Kozielec Z, Pruszyński JJ, Bittel M, Gure AO, Król M, Taciak B : Int J Mol Sci, 2024 - The Molecules Lost New Compounds Binding at the Histamine Site of the NMDA Receptor (NMDA(HA)R).
Armand V : Adv Neur Neur Sci, 2024 - Histamine H1-receptor-mediated modulation of NMDA receptors signaling responses
J-M Arrang, V Armand : Pharmacol Res Perspect, 2024 - Brain inflammation and cognitive decline induced by spinal cord injury can be reversed by spinal cord cell transplants
Q Delarue, A Robac, F Semprez, C Duclos, B Pileyre, P Neveu, C Raimond, G Riou, I Ziane, N Guérout : Brain Behav Immun, 2024 - Spinal microcircuits go through multiphasic homeostatic compensations in a mouse model of motoneuron degeneration.
Nascimento F, Özyurt MG, Halablab K, Bhumbra GS, Caron G, Bączyk M, Zytnicki D, Manuel M, Roselli F, Brownstone R, Beato M : Cell Rep, 2024 - Contributions of Surface and Interface Physical Chemistry to Biology
Ahmed Hamraoui : (preprint), 2024 - Hyperspectral wavefront sensing with a multicore fiber
Baptiste Blochet, Nathalie Lebas, Pascal Berto, Dimitrios Papadopoulos, Marc Guillon : (under review at Nat Commun), 2024 - A Polarimetric Wavefront Imager
Baptiste Blochet, Grégoire Lelu, Miguel A Alonso, Marc Guillon : (under review at Optica), 2024 - Projection-specific integration of convergent thalamic and retrosplenial signals in the presubicular head direction cortex
Louis Richevaux, Dongkyun Lim, Mérie Nassar, Léa Dias Rodrigues, Constanze Mauthe, Ivan Cohen, Nathalie Sol-Foulon, Desdemona Fricker : (preprint), 2024 - Presubicular VIP expressing interneurons receive facilitating excitation from anterior thalamus.
Nassar M, Richevaux L, Lim D, Tayupo D, Martin E, Fricker D : Neuroscience, 2024 - Involvement of kinases in memory consolidation of inhibitory avoidance training.
Montiel I, Bello-Medina PC, Prado-Alcalá RA, Quirarte GL, Verdín-Ruvalcaba LA, Marín-Juárez TA, Medina AC : Rev Neurosci, 2024 - Elucidating the Activation Mechanism of the Proton-sensing GPR68 Receptor.
Matsingos C, Howell LA, McCormick PJ, Fornili A : J Mol Biol, 2024 - The gut, a whistleblower, in the early stages of Parkinson’s disease
Doriane Hazart, Malvyne Rolli-Derkinderen, Brigitte Delhomme, Pascal Derkinderen, Martin Oheim, Clément Ricard : Médecine/sciences, 2024 - Characterizing human astrocyte calcium signaling in a cerebral organoid
Kaitlin Szederkenyi, Liliana Attisano, Martin Oheim, Christopher M Yip : Biophys J, 2024 - L’intestin, lanceur d’alerte, dans les prémices de la maladie de Parkinson
Doriane Hazart, Malvyne Rolli-Derkinderen, Brigitte Delhomme, Pascal Derkinderen, Martin Oheim, Clément Ricard : Médecine/sciences, 2024 - Lesion-induced impairment of therapeutic capacities of olfactory ensheathing cells in an autologous transplantation model for treatment of spinal cord injury
Quentin Delarue, Matthis Brodier, Pauline Neveu, Laurine Moncomble, Alizée Hugede, Axelle Blondin, Amandine Robac, Clémence Raimond, Pamela Lecras, Gaëtan Riou, Nicolas Guérout : (preprint), 2024 - Complementarity between Brillouin signature and Scholte wave for controlled elasticity in fibrillated collagen medium for culture cell
Ahmed Hamraoui, Océane Sénépart, Laurent Belliard : Applied Physics Letters, 2024 - MFSD1 with its accessory subunit GLMP functions as a general dipeptide uniporter in lysosomes
Katharina Esther Julia Jungnickel, Océane Guelle, Miharu Iguchi, Wentao Dong, Vadim Kotov, Florian Gabriel, Cécile Debacker, Julien Dairou, Isabelle McCort-Tranchepain, Nouf N Laqtom, Sze Ham Chan, Akika Ejima, Kenji Sato, David Massa López, Paul Saftig, Ahmad Reza Mehdipour, Monther Abu-Remaileh, Bruno Gasnier, Christian Löw, Markus Damm : Nature Cell Biology, 2024 - Novel Inhibitory Site Revealed by XAP044 Mode of Action on the Metabotropic Glutamate 7 Receptor Venus Flytrap Domain.
Cristiano N, Cabayé A, Brabet I, Glatthar R, Tora A, Goudet C, Bertrand HO, Goupil-Lamy A, Flor PJ, Pin JP, McCort-Tranchepain I, Acher FC : J Med Chem, 2024 - Epitope Identification of an mGlu5 Receptor Nanobody Using Physics-Based Molecular Modeling and Deep Learning Techniques.
Eshak F, Pion L, Scholler P, Nevoltris D, Chames P, Rondard P, Pin JP, Acher FC, Goupil-Lamy A : J Chem Inf Model, 2024 - CBX3 antagonizes IFNγ/STAT1/PD-L1 axis to modulate colon inflammation and CRC chemosensitivity.
Xiang Y, Mata-Garrido J, Fu Y, Desterke C, Batsché E, Hamaï A, Sedlik C, Sereme Y, Skurnik D, Jalil A, Onifarasoaniaina R, Frapy E, Beche JC, Alao R, Piaggio E, Arbibe L, Chang Y : EMBO Mol Med, 2024 - Single-shot digital optical fluorescence phase conjugation through forward multiple-scattering samples
TENGFEI WU, YIXUAN ZHANG, BAPTISTE BLOCHET, PAYVAND ARJMAND, PASCAL BERTO, AND MARC GUILLON : Science advances, 2024 - Multiplexed wavefront sensing with a thin diffuser
Tengfei Wu, Marc Guillon, Gilles Tessier, and Pascal Berto : Optica, 2024 - Design, Synthesis, Pharmacology, and In Silico Studies of (1S,2S,3S)-2-((S)-Amino(carboxy)methyl)-3-(carboxymethyl)cyclopropane-1-carboxylic Acid (LBG30300): A Picomolar Potency Subtype-Selective mGlu(2) Receptor Agonist.
Liu N, Eshak F, Malhaire F, Brabet I, Prézeau L, Renard E, Pin JP, Acher FC, Staudt M, Bunch L : J Med Chem, 2024 - A maximum of two readily releasable vesicles per docking site at a cerebellar single active zone synapse.
Silva M, Tran V, Marty A : Elife, 2024 - A colour-encoded nanometric ruler for axial super-resolution microscopies
Ilya Olevsko, Omer Shavit, Moshe Feldberg, Yossi Abulafia, Adi Salomon, Martin Oheim : Optics Communications, 2024