Publications
Congrats to Floriane and Francine for the cover of JCIM
Congratulation to Floriane ESHAK and Francine ACHER (team 4) for the cover of Journal of Chemical Information and Modeling. Article : Epitope Identification of an mGlu5 Receptor Nanobody Using Physics-Based Molecular Modeling and Deep Learning ...
Congrats to Océane, Cécile and Bruno for their article in Nature Cell Biology
Congrats to Océane Guelle, Cécile Jouffret and Bruno Gasnier, our colleagues Isabelle McCort and Julien Dairou from the chemistry UMR8601 lab, and our collaborators at the University of Kiel and EMBL Hamburg for the Nature Cell Biology paper published o ...
A Colour-Encoded Nanometric Ruler for Axial Super-Resolution Microscopies
Recent progress has boosted the resolving power of optical microscopies to spatial dimensions well below the diffraction limit. Yet, axial super-resolution and axial single-molecule localisation typically require more complicated implementations than t ...
A first step towards truly quantitative TIRF microsopy
Total internal reflection and other near-field optical techniques excel in selectively imaging dynamic processes at or near the basal plasma membrane, e.g., single-receptor or single-vesicle dynamics. However, it has been difficult to quantify TIRF int ...
Characterizing nanometric axial distance with far-field light
A group of researchers around Adi Salomon (BINA Nanocenter, Ramat-Gan, Israel) and Martin Oheim (SPPIN) have developed a simple nanometric calibration tool for axial super-resolution imaging. In a pre-print available on biorXiv, they describe a simpl ...
Our first work on the enteric nervous system, the “brain in the gut” is out!
Our first work on the enteric nervous system, the “brain in the gut” is out! Check out out work at bioRxiv: https://www.biorxiv.org/content/10.1101/2022.06.15.496266 UPDATE (2023/01) : The article has been accepted in Frontiers in Neuroanatomy ...
Understanding the effect of scattered evanescent light
Evanescent-wave scattering is a topic in classical electrodynamics and in the study of colloidal particles near a boundary. However, how such near-surface scattering at sub-cellular refractive-index heterogeneities degrades the excitation confinement ...
A nutrient sensor in the cell’s stomach | INSB (cnrs.fr)
© Solène Lebrun & Bruno Gasnier To stay in good health, cells that no longer divide such as neurons renew their components by degrading them and recycling their building blocks in acidic compartments called lysosomes. These “micro-stomachs” ...
Complex scattered light-field measurement with a simple wavefront-sensor
Wavefront sensors are simple and robust phase sensors at the basis of adaptive optics in astronomy and bio-imaging. Adaptive optics has been introduced in bio-imaging to compensate smooth aberrations mostly arising from the refractive index mismatch a ...
A simple, inexpensive and multi-scale 3-D fluorescent test sample for optical sectioning microscopies
Pyranine-labeled tissue paper, imaged upon 405-nm epifluorescence excitation through a 455LP LP dichroic and 465LP emission filter. Objective ×20/NA0.25. Overlaid are the normalised absorbance (dashed) and emission spectra (through line), respectively. I ...
Fresh from the press
Articles
- Rapid Motor Adaptation via Population-level Modulation of Cerebellar Error Signals
Vinh Nguyen, Brandon M Stell : (preprint), in press - Associative plasticity of granule cell inputs to cerebellar Purkinje cells
Rossella Conti, Céline Auger : (preprint), in press - Combinatorial Sample-and Back-Focal-Plane (BFP) Imaging. Pt. I: Instrument and acquisition parameters affecting BFP images and their analysis
Omer Shavit, Hervé Suaudeau, Carine Julien, Hodaya Klimovsky, Natalia Mañas-Chavernas, Adi Salomon, Martin Oheim : (preprint), 2025 - Managing surface energy dynamics for enhanced axonal growth: An overview of present and future challenges
Sénépart O, Legay C, Hamraoui A : Biophysics Reviews, 2025 - Unveiling the Phenotypic Variability of Macrophages: Insights from Donor Diversity and Pooling Strategies.
Taciak B, Grochowska A, Górczak M, Górka E, Skorzynski M, Białasek M, Rygiel TP, Król M : Int J Mol Sci, 2025 - Harnessing macrophage-drug conjugates for allogeneic cell-based therapy of solid tumors via the TRAIN mechanism.
Taciak B, Bialasek M, Kubiak M, Marszalek I, Gorczak M, Osadchuk O, Kurpiel D, Strzemecki D, Barwik K, Skorzynski M, Nowakowska J, Lipiński W, Kiraga Ł, Brancewicz J, Klopfleisch R, Krzemiński Ł, Gorka E, Smolarska A, Padzinska-Pruszynska I, Siemińska M, Guzek J, Kutner J, Kisiala M, Wozniak K, Parisi G, Piacentini R, Cassetta L, Forrester LM, Bodnar L, Weiss T, Boffi A, Kucharzewska P, Rygiel TP, Krol M : Nat Commun, 2025 - A first morphological and electrophysiological characterization of Fañanas cells of the mouse cerebellum.
Singer A, Trigo F, Vinel L, Gruere O, Llano I, Oheim M : J Physiol, 2025 - Imaging the enteric nervous system
Doriane Hazart, Marwa Moulzir, Brigitte Delhomme, Martin Oheim, Clément Ricard : Frontiers in Neuroanatomy (accepted), 2025 - Fast tissue clearing and volume imaging techniques for anatomy
Clément Ricard, Doriane Hazart, Brigitte Delhomme, Marwa Moulzir, Irina Rakotoson, Martin Oheim : Microscopy Research & Technique (accepted), 2025 - Complementary Speckle Stimulated Emission Depletion Microscopy
Payvand Arjmand, Samlan Chandran Thodika, Elsa Bivas, Haoyang Li, Martin Oheim, Hiroyuki Yoshida, Etienne Brasselet, Marc Guillon : ACS Photonics, 2025 - Ice templating water-stable macroporous polysaccharide hydrogels to mimic plant stems.
Komiyama K, Allard M, Eschenbrenner C, Sicard C, Hamraoui A, Fernandes F : Journal of Materials Chemistry B, 2025 - Breast Cancer Plasticity after Chemotherapy Highlights the Need for Re-Evaluation of Subtyping in Residual Cancer and Metastatic Tissues.
Padzińska-Pruszyńska IB, Akbar MW, Isbilen M, Górka E, Kucukkaraduman B, Canlı SD, Dedeoğlu E, Azizolli S, Cela I, Akcay AG, Hakanoglu H, Bodnar L, Cierniak S, Kozielec Z, Pruszyński JJ, Bittel M, Gure AO, Król M, Taciak B : Int J Mol Sci, 2024 - The Molecules Lost New Compounds Binding at the Histamine Site of the NMDA Receptor (NMDA(HA)R).
Armand V : Adv Neur Neur Sci, 2024 - Histamine H1-receptor-mediated modulation of NMDA receptors signaling responses
J-M Arrang, V Armand : Pharmacol Res Perspect, 2024 - Brain inflammation and cognitive decline induced by spinal cord injury can be reversed by spinal cord cell transplants
Q Delarue, A Robac, F Semprez, C Duclos, B Pileyre, P Neveu, C Raimond, G Riou, I Ziane, N Guérout : Brain Behav Immun, 2024 - Spinal microcircuits go through multiphasic homeostatic compensations in a mouse model of motoneuron degeneration.
Nascimento F, Özyurt MG, Halablab K, Bhumbra GS, Caron G, Bączyk M, Zytnicki D, Manuel M, Roselli F, Brownstone R, Beato M : Cell Rep, 2024 - Contributions of Surface and Interface Physical Chemistry to Biology
Ahmed Hamraoui : (preprint), 2024 - Hyperspectral wavefront sensing with a multicore fiber
Baptiste Blochet, Nathalie Lebas, Pascal Berto, Dimitrios Papadopoulos, Marc Guillon : (under review at Nat Commun), 2024 - A Polarimetric Wavefront Imager
Baptiste Blochet, Grégoire Lelu, Miguel A Alonso, Marc Guillon : (under review at Optica), 2024 - Projection-specific integration of convergent thalamic and retrosplenial signals in the presubicular head direction cortex
Louis Richevaux, Dongkyun Lim, Mérie Nassar, Léa Dias Rodrigues, Constanze Mauthe, Ivan Cohen, Nathalie Sol-Foulon, Desdemona Fricker : (preprint), 2024 - Presubicular VIP expressing interneurons receive facilitating excitation from anterior thalamus.
Nassar M, Richevaux L, Lim D, Tayupo D, Martin E, Fricker D : Neuroscience, 2024 - Involvement of kinases in memory consolidation of inhibitory avoidance training.
Montiel I, Bello-Medina PC, Prado-Alcalá RA, Quirarte GL, Verdín-Ruvalcaba LA, Marín-Juárez TA, Medina AC : Rev Neurosci, 2024 - Elucidating the Activation Mechanism of the Proton-sensing GPR68 Receptor.
Matsingos C, Howell LA, McCormick PJ, Fornili A : J Mol Biol, 2024 - The gut, a whistleblower, in the early stages of Parkinson’s disease
Doriane Hazart, Malvyne Rolli-Derkinderen, Brigitte Delhomme, Pascal Derkinderen, Martin Oheim, Clément Ricard : Médecine/sciences, 2024 - Characterizing human astrocyte calcium signaling in a cerebral organoid
Kaitlin Szederkenyi, Liliana Attisano, Martin Oheim, Christopher M Yip : Biophys J, 2024 - L’intestin, lanceur d’alerte, dans les prémices de la maladie de Parkinson
Doriane Hazart, Malvyne Rolli-Derkinderen, Brigitte Delhomme, Pascal Derkinderen, Martin Oheim, Clément Ricard : Médecine/sciences, 2024 - Lesion-induced impairment of therapeutic capacities of olfactory ensheathing cells in an autologous transplantation model for treatment of spinal cord injury
Quentin Delarue, Matthis Brodier, Pauline Neveu, Laurine Moncomble, Alizée Hugede, Axelle Blondin, Amandine Robac, Clémence Raimond, Pamela Lecras, Gaëtan Riou, Nicolas Guérout : (preprint), 2024 - Complementarity between Brillouin signature and Scholte wave for controlled elasticity in fibrillated collagen medium for culture cell
Ahmed Hamraoui, Océane Sénépart, Laurent Belliard : Applied Physics Letters, 2024 - MFSD1 with its accessory subunit GLMP functions as a general dipeptide uniporter in lysosomes
Katharina Esther Julia Jungnickel, Océane Guelle, Miharu Iguchi, Wentao Dong, Vadim Kotov, Florian Gabriel, Cécile Debacker, Julien Dairou, Isabelle McCort-Tranchepain, Nouf N Laqtom, Sze Ham Chan, Akika Ejima, Kenji Sato, David Massa López, Paul Saftig, Ahmad Reza Mehdipour, Monther Abu-Remaileh, Bruno Gasnier, Christian Löw, Markus Damm : Nature Cell Biology, 2024 - Novel Inhibitory Site Revealed by XAP044 Mode of Action on the Metabotropic Glutamate 7 Receptor Venus Flytrap Domain.
Cristiano N, Cabayé A, Brabet I, Glatthar R, Tora A, Goudet C, Bertrand HO, Goupil-Lamy A, Flor PJ, Pin JP, McCort-Tranchepain I, Acher FC : J Med Chem, 2024 - Epitope Identification of an mGlu5 Receptor Nanobody Using Physics-Based Molecular Modeling and Deep Learning Techniques.
Eshak F, Pion L, Scholler P, Nevoltris D, Chames P, Rondard P, Pin JP, Acher FC, Goupil-Lamy A : J Chem Inf Model, 2024 - CBX3 antagonizes IFNγ/STAT1/PD-L1 axis to modulate colon inflammation and CRC chemosensitivity.
Xiang Y, Mata-Garrido J, Fu Y, Desterke C, Batsché E, Hamaï A, Sedlik C, Sereme Y, Skurnik D, Jalil A, Onifarasoaniaina R, Frapy E, Beche JC, Alao R, Piaggio E, Arbibe L, Chang Y : EMBO Mol Med, 2024 - Single-shot digital optical fluorescence phase conjugation through forward multiple-scattering samples
TENGFEI WU, YIXUAN ZHANG, BAPTISTE BLOCHET, PAYVAND ARJMAND, PASCAL BERTO, AND MARC GUILLON : Science advances, 2024 - Multiplexed wavefront sensing with a thin diffuser
Tengfei Wu, Marc Guillon, Gilles Tessier, and Pascal Berto : Optica, 2024 - Design, Synthesis, Pharmacology, and In Silico Studies of (1S,2S,3S)-2-((S)-Amino(carboxy)methyl)-3-(carboxymethyl)cyclopropane-1-carboxylic Acid (LBG30300): A Picomolar Potency Subtype-Selective mGlu(2) Receptor Agonist.
Liu N, Eshak F, Malhaire F, Brabet I, Prézeau L, Renard E, Pin JP, Acher FC, Staudt M, Bunch L : J Med Chem, 2024 - A maximum of two readily releasable vesicles per docking site at a cerebellar single active zone synapse.
Silva M, Tran V, Marty A : Elife, 2024 - A colour-encoded nanometric ruler for axial super-resolution microscopies
Ilya Olevsko, Omer Shavit, Moshe Feldberg, Yossi Abulafia, Adi Salomon, Martin Oheim : Optics Communications, 2024