Publications
Congrats to Floriane and Francine for the cover of JCIM
Congratulation to Floriane ESHAK and Francine ACHER (team 4) for the cover of Journal of Chemical Information and Modeling. Article : Epitope Identification of an mGlu5 Receptor Nanobody Using Physics-Based Molecular Modeling and Deep Learning ...
Congrats to Océane, Cécile and Bruno for their article in Nature Cell Biology
Congrats to Océane Guelle, Cécile Jouffret and Bruno Gasnier, our colleagues Isabelle McCort and Julien Dairou from the chemistry UMR8601 lab, and our collaborators at the University of Kiel and EMBL Hamburg for the Nature Cell Biology paper published o ...
A Colour-Encoded Nanometric Ruler for Axial Super-Resolution Microscopies
Recent progress has boosted the resolving power of optical microscopies to spatial dimensions well below the diffraction limit. Yet, axial super-resolution and axial single-molecule localisation typically require more complicated implementations than t ...
A first step towards truly quantitative TIRF microsopy
Total internal reflection and other near-field optical techniques excel in selectively imaging dynamic processes at or near the basal plasma membrane, e.g., single-receptor or single-vesicle dynamics. However, it has been difficult to quantify TIRF int ...
Characterizing nanometric axial distance with far-field light
A group of researchers around Adi Salomon (BINA Nanocenter, Ramat-Gan, Israel) and Martin Oheim (SPPIN) have developed a simple nanometric calibration tool for axial super-resolution imaging. In a pre-print available on biorXiv, they describe a simpl ...
Our first work on the enteric nervous system, the “brain in the gut” is out!
Our first work on the enteric nervous system, the “brain in the gut” is out! Check out out work at bioRxiv: https://www.biorxiv.org/content/10.1101/2022.06.15.496266 UPDATE (2023/01) : The article has been accepted in Frontiers in Neuroanatomy ...
Understanding the effect of scattered evanescent light
Evanescent-wave scattering is a topic in classical electrodynamics and in the study of colloidal particles near a boundary. However, how such near-surface scattering at sub-cellular refractive-index heterogeneities degrades the excitation confinement ...
A nutrient sensor in the cell’s stomach | INSB (cnrs.fr)
© Solène Lebrun & Bruno Gasnier To stay in good health, cells that no longer divide such as neurons renew their components by degrading them and recycling their building blocks in acidic compartments called lysosomes. These “micro-stomachs” ...
Complex scattered light-field measurement with a simple wavefront-sensor
Wavefront sensors are simple and robust phase sensors at the basis of adaptive optics in astronomy and bio-imaging. Adaptive optics has been introduced in bio-imaging to compensate smooth aberrations mostly arising from the refractive index mismatch a ...
A simple, inexpensive and multi-scale 3-D fluorescent test sample for optical sectioning microscopies
Pyranine-labeled tissue paper, imaged upon 405-nm epifluorescence excitation through a 455LP LP dichroic and 465LP emission filter. Objective ×20/NA0.25. Overlaid are the normalised absorbance (dashed) and emission spectra (through line), respectively. I ...
Fresh from the press
Articles
- Rapid Motor Adaptation via Population-level Modulation of Cerebellar Error Signals
Vinh Nguyen, Brandon M Stell : (preprint), in press - Associative plasticity of granule cell inputs to cerebellar Purkinje cells
Rossella Conti, Céline Auger : (preprint), in press - A Colour-Encoded Nanometric Ruler for Axial Super-Resolution Microscopies
Ilya Olevsko, Omer Shavit, Moshe Feldberg, Yossi Abulafia, Adi Salomon, Martin Oheim : (preprint), in press - Lesion-induced impairment of therapeutic capacities of olfactory ensheathing cells in an autologous transplantation model for treatment of spinal cord injury
Quentin Delarue, Matthis Brodier, Pauline Neveu, Laurine Moncomble, Alizée Hugede, Axelle Blondin, Amandine Robac, Clémence Raimond, Pamela Lecras, Gaëtan Riou, Nicolas Guérout : (preprint), 2024 - Complementarity between Brillouin signature and Scholte wave for controlled elasticity in fibrillated collagen medium for culture cell
Ahmed Hamraoui, Océane Sénépart, Laurent Belliard : Applied Physics Letters - Materials, Accepted, 2024 - MFSD1 with its accessory subunit GLMP functions as a general dipeptide uniporter in lysosomes
Katharina Esther Julia Jungnickel, Océane Guelle, Miharu Iguchi, Wentao Dong, Vadim Kotov, Florian Gabriel, Cécile Debacker, Julien Dairou, Isabelle McCort-Tranchepain, Nouf N Laqtom, Sze Ham Chan, Akika Ejima, Kenji Sato, David Massa López, Paul Saftig, Ahmad Reza Mehdipour, Monther Abu-Remaileh, Bruno Gasnier, Christian Löw, Markus Damm : Nature Cell Biology, 2024 - Novel Inhibitory Site Revealed by XAP044 Mode of Action on the Metabotropic Glutamate 7 Receptor Venus Flytrap Domain.
Cristiano N, Cabayé A, Brabet I, Glatthar R, Tora A, Goudet C, Bertrand HO, Goupil-Lamy A, Flor PJ, Pin JP, McCort-Tranchepain I, Acher FC : J Med Chem, 2024 - Epitope Identification of an mGlu5 Receptor Nanobody Using Physics-Based Molecular Modeling and Deep Learning Techniques.
Eshak F, Pion L, Scholler P, Nevoltris D, Chames P, Rondard P, Pin JP, Acher FC, Goupil-Lamy A : J Chem Inf Model, 2024 - Ice templating water-stable macroporous polysaccharide hydrogels to mimic plant stems.
Komiyama K, Allard M, Eschenbrenner C, Sicard C, Hamraoui A, Fernandes F : (preprint), 2024 - CBX3 antagonizes IFNγ/STAT1/PD-L1 axis to modulate colon inflammation and CRC chemosensitivity.
Xiang Y, Mata-Garrido J, Fu Y, Desterke C, Batsché E, Hamaï A, Sedlik C, Sereme Y, Skurnik D, Jalil A, Onifarasoaniaina R, Frapy E, Beche JC, Alao R, Piaggio E, Arbibe L, Chang Y : EMBO Mol Med, 2024 - Single-shot digital optical fluorescence phase conjugation through forward multiple-scattering samples
TENGFEI WU, YIXUAN ZHANG, BAPTISTE BLOCHET, PAYVAND ARJMAND, PASCAL BERTO, AND MARC GUILLON : Science advances, 2024 - Multiplexed wavefront sensing with a thin diffuser
Tengfei Wu, Marc Guillon, Gilles Tessier, and Pascal Berto : Optica, 2024 - Design, Synthesis, Pharmacology, and In Silico Studies of (1S,2S,3S)-2-((S)-Amino(carboxy)methyl)-3-(carboxymethyl)cyclopropane-1-carboxylic Acid (LBG30300): A Picomolar Potency Subtype-Selective mGlu(2) Receptor Agonist.
Liu N, Eshak F, Malhaire F, Brabet I, Prézeau L, Renard E, Pin JP, Acher FC, Staudt M, Bunch L : J Med Chem, 2024 - A maximum of two readily releasable vesicles per docking site at a cerebellar single active zone synapse.
Silva M, Tran V, Marty A : Elife, 2024 - Advances in Spinal Cord Neuromodulation: The Integration of Neuroengineering, Computational Approaches, and Innovative Conceptual Frameworks.
Pradat PF, Hayon D, Blancho S, Neveu P, Khamaysa M, Guerout N : J Pers Med, 2023 - Mesenchymal calcium waves underpin intestinal smooth muscle differentiation
Chevalier N R, Zig L, Gomis A, Amedzrovi Agbesi R, Pontoizeau L, Eude-Le Parco I, Rouach N, Arnoux I, De Santa Barbara P, Faure S : Communications Biology, 2023 - Electrical and Mechanosensitive Activity of the Mouse Fetal Enteric Nervous System
Amedzrovi Agbesi R, Spencer N, Hebberd T, Chevalier N R : J Physiol, 2023 - Multisensory gaze stabilization in response to subchronic alteration of vestibular type I hair cells.
Schenberg L, Palou A, Simon F, Bonnard T, Barton CE, Fricker D, Tagliabue M, Llorens J, Beraneck M : Elife, 2023 - Beneficial Effect of Bee Venom and Its Major Components on Facial Nerve Injury Induced in Mice.
Er-Rouassi H, Bakour M, Touzani S, Vilas-Boas M, Falcão S, Vidal C, Lyoussi B : Biomolecules, 2023 - PTBP1 regulates injury responses and sensory pathways in adult peripheral neurons.
Alber S, Di Matteo P, Zdradzinski MD, Dalla Costa I, Medzihradszky KF, Kawaguchi R, Di Pizio A, Freund P, Panayotis N, Marvaldi L, Doron-Mandel E, Okladnikov N, Rishal I, Nevo R, Coppola G, Lee SJ, Sahoo PK, Burlingame AL, Twiss JL, Fainzilber M : Sci Adv, 2023 - Depolarization-induced bursts of miniature synaptic currents in individual synapses of developing cerebellum.
Le Guellec B, Gomez LC, Malagon G, Collin T, Marty A : J Gen Physiol, 2023 - Prioritized docking of synaptic vesicles provided by a rapid recycling pathway
Tran V, Silva M, Marty A : IScience, 2023 - Bumetanide increases postsynaptic inhibition after chronic SCI and decreases presynaptic inhibition with step-training.
Caron G, Bilchak J, Côté MP : J Physiol, 2023 - KCa1.1 channels contribute to optogenetically driven post-stimulation silencing in cerebellar molecular layer interneurons.
Kassa M, Bradley J, Jalil A, Llano I : J Gen Physiol, 2023 - Characterizing nanometric thin films with far-field light
Klimovsky H, Shavit O, Julien C, Olevsko I, Hamode M, Abulafia Y, Suaudeau H, Armand V, Oheim M, Salomon A : Adv Opt Mater, 2023