News
09/11 – Gerhard Schuetz – Following T cell antigen recognition molecule by molecule
SPPIN’s webinar 2021, 09 NOVEMBER at 10h, online – Ask link to a SPPIN member. Gerhard Schuetz – Vienna University of Technology – Institute of Applied Physics – Biophysics Following T cell antigen recognition molecule by m ...
16/11 – Jérôme Lecoq : Removing independent noise in systems neuroscience data using DeepInterpolation and some updates on the OpenScope platform
SPPIN’s webinar 2021, 16 NOVEMBER at 16h, online – Ask link to a SPPIN member. Jérôme Lecoq, Ph.D. Principal Scientist, Allen Institute for Brain Science, United States Removing independent noise in systems neuroscience data using DeepInterpol ...
The SPPIN welcomes Marc Guillon as new P.I.
In his Singular Imaging (SingIng) group, Marc will aim at developing novel imaging capabilities based on a in-depth study of singular optics and complex media. Marc’s group has emerged from within the SPPIN laboratory following the demand for de ...
Understanding the effect of scattered evanescent light
Evanescent-wave scattering is a topic in classical electrodynamics and in the study of colloidal particles near a boundary. However, how such near-surface scattering at sub-cellular refractive-index heterogeneities degrades the excitation confinement ...
A nutrient sensor in the cell’s stomach | INSB (cnrs.fr)
© Solène Lebrun & Bruno Gasnier To stay in good health, cells that no longer divide such as neurons renew their components by degrading them and recycling their building blocks in acidic compartments called lysosomes. These “micro-stomachs” ...
Complex scattered light-field measurement with a simple wavefront-sensor
Wavefront sensors are simple and robust phase sensors at the basis of adaptive optics in astronomy and bio-imaging. Adaptive optics has been introduced in bio-imaging to compensate smooth aberrations mostly arising from the refractive index mismatch a ...
06/07 – Nicolas Panayotis : Elucidating the role of Importins Nuclear Transport Factors in CNS Functions
SPPIN’s webinar winter-spring 2021, 6 JULLY at 10h30, online – Ask link to a SPPIN member. Nicolas Panayotis : Molecular Neurobiologist at the Weizmann Institute of Science, Rehovot, Israel Elucidating the role of Importins Nuclear Transport ...
30/06 – Niccolò Zampieri : Proprioception and spinal circuits for postural control
UFR / SPPIN’s webinar winter-spring 2021, UNUSUAL TIME – 30th June at 11h30, room R229. Niccolò Zampieri, Max-Delbrück-Centrum für Molekulare Medizin (MDC) – Berlin – Germany Proprioception and spinal circuits for postural con ...
29/06 – Michela Di Virgilio : Principles and Mechanisms of Genome Diversification & Integrity
UFR / SPPIN’s webinar winter-spring 2021, UNUSUAL TIME – 29th June at 11h30, room R229. Dr. Michela Di Virgilio, Max-Delbrück-Centrum für Molekulare Medizin (MDC), Berlin, Germany Principles and Mechanisms of Genome Diversification & I ...
A simple, inexpensive and multi-scale 3-D fluorescent test sample for optical sectioning microscopies
Pyranine-labeled tissue paper, imaged upon 405-nm epifluorescence excitation through a 455LP LP dichroic and 465LP emission filter. Objective ×20/NA0.25. Overlaid are the normalised absorbance (dashed) and emission spectra (through line), respectively. I ...
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Fresh from the press
Articles
- Characterizing nanometric thin films with far-field light
Klimovsky H, Shavit O, Julien C, Olevsko I, Hamode M, Abulafia Y, Suaudeau H, Armand V, Oheim M, Salomon A : BioRxiv, in press - Nanoscopy of Aluminum Plasmonic Cavities by Cathodoluminescence and Second-Harmonic Generation
Tchiya Zar, Martin Oheim, Adi Salomon : Adv Photonics Res, in press - Label-free, fast, 2-photon volume imaging of the structural organization of peripheral neurons and glia in the enteric ganglia
Doriane Hazart, Brigitte Delhomme, Martin Oheim, Clément Ricard : Preprint, in press - Enzyme replacement therapy: current challenges and drug delivery prospects via extracellular vesicles
Silva A K, Sagné C, Gazeau F, Abasolo I : Rare Disease and Orphan Drugs Journal, 2022 - Small-Molecule 3D Ligand for RNA Recognition: Tuning Selectivity through Scaffold Hopping.
Felder S, Sagné C, Benedetti E, Micouin L : ACS Chem Biol, 2022 - State-of-the-art therapies for Rett syndrome.
Panayotis N, Ehinger Y, Felix MS, Roux JC : Dev Med Child Neurol, 2022 - The SELENOT mimetic PSELT promotes nerve regeneration by increasing axonal myelination in a facial nerve injury model in female rats.
Pothion H, Lihrmann I, Duclos C, Riou G, Cartier D, Boukhzar L, Lefranc B, Leprince J, Guérout N, Marie JP, Anouar Y : J Neurosci Res, 2022 - 3D nanoparticle superlocalization with a thin diffuser
Tengfei Wu, Marc Guillon, Clemence Gentner, Herve Rigneault, Gilles Tessier, Pierre Bon, Pascal Berto : Opt Lett, 2022 - Carboxypeptidase E Independently Changes Microtubule Glutamylation, Dendritic Branching, and Neuronal Migration.
Liang C, Carrel D, Singh NK, Hiester LL, Fanget I, Kim H, Firestein BL : ASN Neuro, 2022 - Metabotropic glutamate receptor orthosteric ligands and their binding sites.
Acher FC, Cabayé A, Eshak F, Goupil-Lamy A, Pin JP : Neuropharmacology, 2022 - β-sitosterol reduces anxiety and synergizes with established anxiolytic drugs in mice.
Panayotis N, Freund PA, Marvaldi L, Shalit T, Brandis A, Mehlman T, Tsoory MM, Fainzilber M : Cell Rep Med, 2021 - Repetitive Trans Spinal Magnetic Stimulation Improves Functional Recovery and Tissue Repair in Contusive and Penetrating Spinal Cord Injury Models in Rats.
Robac A, Neveu P, Hugede A, Garrido E, Nicol L, Delarue Q, Guérout N : Biomedicines, 2021 - RNA Profiling of Mouse Ependymal Cells after Spinal Cord Injury Identifies the Oncostatin Pathway as a Potential Key Regulator of Spinal Cord Stem Cell Fate.
Chevreau R, Ghazale H, Ripoll C, Chalfouh C, Delarue Q, Hemonnot-Girard AL, Mamaeva D, Hirbec H, Rothhut B, Wahane S, Perrin FE, Noristani HN, Guerout N, Hugnot JP : Cells, 2021 - Plasticity of the Injured Spinal Cord.
Guérout N : Cells, 2021 - Comparison of the effects of two therapeutic strategies based on olfactory ensheathing cell transplantation and repetitive magnetic stimulation after spinal cord injury in female mice.
Delarue Q, Robac A, Massardier R, Marie JP, Guérout N : J Neurosci Res, 2021 - Spinal cord injury: can we repair spinal cord non-invasively by using magnetic stimulation?
Delarue Q, Chalfouh C, Guérout N : Neural Regen Res, 2021 - Exercise-Induced Plasticity in Signaling Pathways Involved in Motor Recovery after Spinal Cord Injury.
Bilchak JN, Caron G, Côté MP : Int J Mol Sci, 2021 - Optoproteomics elucidates the interactome of L-type amino acid transporter 3 (LAT3).
Wang L, Sun X, Lu L, Marie A, Carrel D, Zhao S, Mille C, Song Q, Zhang Y, Ye S : Chem Commun (Camb), 2021 - Optoproteomics elucidates the interactome of L-type amino acid transporter 3 (LAT3).
Wang L, Sun X, Lu L, Marie A, Carrel D, Zhao S, Mille C, Song Q, Zhang Y, Ye S : Chem Commun (Camb), 2021 - Astroglial Cx30 differentially impacts synaptic activity from hippocampal principal cells and interneurons.
Hardy E, Cohen-Salmon M, Rouach N, Rancillac A : Glia, 2021 - Adult medial habenula neurons require GDNF receptor GFRα1 for synaptic stability and function.
Fernández-Suárez D, Krapacher FA, Pietrajtis K, Andersson A, Kisiswa L, Carrier-Ruiz A, Diana MA, Ibáñez CF : PLoS Biol, 2021 - A nanobody activating metabotropic glutamate receptor 4 discriminates between homo- and heterodimers.
Haubrich J, Font J, Quast RB, Goupil-Lamy A, Scholler P, Nevoltris D, Acher F, Chames P, Rondard P, Prézeau L, Pin JP : Proc Natl Acad Sci U S A, 2021 - LSP2-9166, an orthosteric mGlu4 and mGlu7 receptor agonist, reduces cocaine self-administration under a progressive ratio schedule in rats.
De Sa Nogueira D, Bourdy R, Filliol D, Quessada C, McCort-Tranchepain I, Acher F, Zwiller J, Romieu P, Befort K : Neurosci Lett, 2021 - Chromato-axial memory effect in step-index multimode fibers
Devaud L, Guillon M, Gusachenko I, Gigan S : APL Photonics, 2021 - Disrupting D1-NMDA or D2-NMDA receptor heteromerization prevents cocaine’s rewarding effects but preserves natural reward processing.
Andrianarivelo A, Saint-Jour E, Pousinha P, Fernandez SP, Petitbon A, De Smedt-Peyrusse V, Heck N, Ortiz V, Allichon MC, Kappès V, Betuing S, Walle R, Zhu Y, Joséphine C, Bemelmans AP, Turecki G, Mechawar N, Javitch JA, Caboche J, Trifilieff P, Barik J, Vanhoutte P : Sci Adv, 2021 - Cell-type- and region-specific modulation of cocaine seeking by micro-RNA-1 in striatal projection neurons.
Forget B, Garcia EM, Godino A, Rodriguez LD, Kappes V, Poirier P, Andrianarivelo A, Marchan ES, Allichon MC, Marias M, Vanhoutte P, Girault JA, Maldonado R, Caboche J : Mol Psychiatry, 2021 - Npas4 regulates medium spiny neuron physiology and gates cocaine-induced hyperlocomotion.
Lissek T, Andrianarivelo A, Saint-Jour E, Allichon MC, Bauersachs HG, Nassar M, Piette C, Pruunsild P, Tan YW, Forget B, Heck N, Caboche J, Venance L, Vanhoutte P, Bading H : EMBO Rep, 2021 - Calcium-dependent docking of synaptic vesicles.
Silva M, Tran V, Marty A : Trends Neurosci, 2021 - Optometry for a short-sighted microscope.
Julien C, Oheim M : Biophys J, 2021 - Arginine-selective modulation of the lysosomal transporter PQLC2 through a gate-tuning mechanism.
Leray X, Conti R, Li Y, Debacker C, Castelli F, Fenaille F, Zdebik AA, Pusch M, Gasnier B : Proc Natl Acad Sci U S A, 2021 - A role for BDNF- and NMDAR-induced lysosomal recruitment of mTORC1 in the regulation of neuronal mTORC1 activity.
Khamsing D, Lebrun S, Fanget I, Larochette N, Tourain C, de Sars V, Brunstein M, Oheim M, Carrel D, Darchen F, Desnos C : Mol Brain, 2021 - Comments on the article by Jensen et al. (2020).
Manuel M, Zytnicki D : J Physiol, 2021 - Plug-and-socket mechanisms in nutrient sensing by lysosomal amino acid transporters.
Gasnier B : Proc Natl Acad Sci U S A, 2021 - Free sialic acid storage disorder: Progress and promise.
Huizing M, Hackbarth ME, Adams DR, Wasserstein M, Patterson MC, Walkley SU, Gahl WA, FSASD Consortium : Neurosci Lett, 2021 - Reference-less complex wavefields characterization with a high-resolution wavefront sensor
Wu T, Berto P, Guillon M : Applied Physics Letters, 2021 - Synaptic disruption and CREB-regulated transcription are restored by K channel blockers in ALS.
Catanese A, Rajkumar S, Sommer D, Freisem D, Wirth A, Aly A, Massa-López D, Olivieri A, Torelli F, Ioannidis V, Lipecka J, Guerrera IC, Zytnicki D, Ludolph A, Kabashi E, Mulaw MA, Roselli F, Böckers TM : EMBO Mol Med, 2021 - A simple, inexpensive and multi-scale 3-D fluorescent test sample for optical sectioning microscopies.
Olevsko I, Szederkenyi K, Corridon J, Au A, Delhomme B, Bastien T, Fernandes J, Yip C, Oheim M, Salomon A : Microsc Res Tech, 2021 - Astrocytes respond to a neurotoxic Aβ fragment with state-dependent Ca alteration and multiphasic transmitter release.
Pham C, Hérault K, Oheim M, Maldera S, Vialou V, Cauli B, Li D : Acta Neuropathol Commun, 2021 - Three-dimensional broadband light beam manipulation in forward scattering samples
Payvand Arjmand, Ori Katz, Sylvain Gigan, Marc Guillon : Opt Express, 2021 - Is there hope that transpinal direct current stimulation corrects motoneuron excitability and provides neuroprotection in amyotrophic lateral sclerosis?
Bączyk M, Krutki P, Zytnicki D : Physiol Rep, 2021 - Enhancing KCC2 activity decreases hyperreflexia and spasticity after chronic spinal cord injury.
Bilchak J, Yeakle K, Caron G, Malloy D, Côté MP : Exp Neurol, 2021