News
SPPIN Team Received Claude Pompidou Prize for Breakthrough Method in Early Parkinson’s Detection
Members of the Brain Biophysics team and shared SPPIN staff who participated in the research. Translation of the press release from the Claude Pompidou Foundation for Research on Alzheimer’s Disease and Other Neurodegenerative Diseases: For i ...
16 October 2025 – Ilya OLEVSKO – Nano Bead Emitters: A Versatile Toolkit for Advanced Optical Thin Films
Dr. Ilya OLEVSKO, Bar-Ilan University and BINA Nanocenter SPPIN’s webinar 2025, 16 October at 10h, SPPIN common room, 3rd floor Nano Bead Emitters: A Versatile Toolkit for Advanced Optical Thin Films My seminar will introduce the Nano Bead ...
The SPPIN’s “Biophysics of the Brain” team wins the Claude Pompidou Prize for research into neurodegenerative disease
For its 13th edition, the Claude Pompidou Prize, worth €100,000, recognized the work of the “Biophysics of the Brain” team at the CNRS-SPPIN, Saints-Pères Paris Institute for the Neurosciences at Université Paris Cité, led by Martin Oheim. ...
Season 2025/26 of the Neural Networking Night seminar series (co-organized by SPPIN member)
We are excited to announce the new season of the Neural Networking Night seminar series! We look forward to welcoming you at Le Piano Vache for presentations by a fantastic line-up of neuroscientists from across Île-de-France. The new cycle will fea ...
Le SPPIN rencontre l’art en septembre !
L’équipe 8 “Orientation & Coordination” organise un événement de médiation scientifique autour des Neurosciences, le 22-28 Septembre 2025, à la Capitainerie de l’Isle, 26 rue Chanoinesse, 75004 Paris. Plongez dans l’unive ...
EMBO SHORT TERM FELLOW Keren Zahlenchuck joins the SPPIN to work on advanced beam shaping strategies for mesoscale light-sheet microscopy
Keren Zahlenchuck is going to rejoin SPPIN’s team “Biophysics of the brain” (Oheim, https://www.sppin.fr/) from 1 September onwards. Keren is the recipient of an EMBO short term fellowship and will be working with Brieuc Chauvin, Hugo Touja ...
4 September 2025 – Marc DHENAIN – Pseudo-prions to treat neurodegenerative diseases
Dr. Marc DHENAIN, Neuro-Bicêtre, Bicêtre Hospital, Le Kremlin Bicêtre SPPIN’s webinar 2025, 4 September at 11h, SPPIN common room, 3rd floor Pseudo-prions to treat neurodegenerative diseases Alzheimer’s disease is the result ...
10 June 2025 – Stephanie RUDOLPH – A Mechanism for Amplifying Sparse Neuromodulatory Signals in Electrically Coupled Interneuron Networks
Prof Stephanie RUDOLPH, Albert Einstein College of Medicine, New York SPPIN’s webinar 2025, 10 June at 11h, SPPIN common room, 3rd floor A Mechanism for Amplifying Sparse Neuromodulatory Signals in Electrically Coupled Interneuron Networks ...
20 Mai 2025 – Alexandra FRAGOLA – Fast adaptive optics light-sheet microscopy for in vivo high-resolution imaging at depth
Prof Alexandra FRAGOLA, ISMO, Université Paris Saclay (Orsay) SPPIN’s webinar 2024, 20 May at 11h, SPPIN common room, 3rd floor Fast adaptive optics light-sheet microscopy for in vivo high-resolution imaging at depth The study of fast biol ...
The Association Française du Syndrome de Rett supports Nicolas PANAYOTIS
Congratulations to Nicolas PANAYOTIS (Team 7) who was awarded a 3-years Research Grant by the French Rett Syndrome Patient Advocacy Organization “Association Française du Syndrome de Rett” (or AFSR). Funded project: NewMOTORS ‘Developmen ...
Next seminars
Fresh from the press
Articles
- Molecular basis of Salla Disease: R39C Mutation Effects on the Lysosomal Transporter Sialin
Christos Matsingos, Isaure Lot, Malaury Vaz, Jade Mailliart, Meryam Boulayat, Cécile Debacker, Anne Goupil-Lamy, Bruno Gasnier, Francine C Acher, Christine Anne : (preprint), 2026 - Increased Osteoclast Activity Contributes to Bone Resorption and Osteopenia in a Rett Syndrome Mouse Model
Samee N, Belz L, Narboux-Nême N, Roux J-C, Panayotis N, Levi G : Cells, 2026 - Spinal motoneuron excitability is homeostatically regulated through β-adrenergic neuromodulation in wild-type and presymptomatic SOD1 mice.
Antonucci S, Caron G, Dikwella N, Krishnamurthy SS, Harster A, Wasicki B, Zarrin H, Tahanis A, Heuvel FO, Danner SM, Ludolph AC, Grycz K, Bączyk M, Zytnicki D, Roselli F : Prog Neurobiol, 2026 - Motoneurons Inhibitory Synapses Homeostatically Respond to Neuronal Activity and Modulate Amyotrophic Lateral Sclerosis Pathogenesis.
Halablab K, Yartas G, Dikwella N, Aousji O, Ozkan B, Jan C, Wiesner D, Danner SM, Caron G, Zytnicki D, Roselli F : J Neurosci, 2026 - From Gene to Hope: Rett Syndrome and the Rise of Molecular Therapies
Yoann Leblay, Marie-Solenne Felix, Jean-Christophe Roux, Nicolas Panayotis : Mol Diagn Ther, 2026 - Repetitive Trans-spinal magnetic stimulation Promotes Repair in Inflammatory Spinal Cord Injury Through Sex-Dependent Immune Modulation
F Semprez, I Ziane, A Du, I Istre, L Dupuis, L Moncomble, P Neveu, C Raimond, A Fernandes, J Dorange, Q Delarue, N Guérout : J Neuroinflammation, 2026 - Prolonged Repetitive Trans-Spinal Magnetic Stimulation Promotes Superior Functional Recovery After Severe Spinal Cord Injury in Rats.
Garrido E, Robac A, Hugede A, Neveu P, Delarue Q, Marie JP, Derrey S, Guérout N : J Neurotrauma, 2026 - Pharmacological activity of a new ligand binding at the histamine site of the NMDA receptor in rodents.
Burban A, Faucard R, Armand V : Eur J Pharmacol, 2026 - Subcellular depletion of importin β1 impairs presynaptic local translation and spatial memory
Philip A Freund, Nicolas Panayotis, Pingan Yuanxiang, Sebastian Samer, Leilah Otikovs, Riki Kawaguchi, Juan Oses-Prieto, Talieh Zomorrodinia, Ida Rishal, Michaela Schweizer, Michael Tsoory, Katarzyna M Grochowska, Anna Karpova, Alma L Burlingame, Michael R Kreutz, Mike Fainzilber : Science Signaling, 2026 - Light as a feather: A novel approach for whole- feather microstructure imaging through tissue clearing and autofluorescence imaging
Marwa Moulzir, Doriane Hazart, Brigitte Delhomme, Martin Oheim, Clément Ricard : Annals of Anatomy - Anatomischer Anzeiger, 2026 - Label-free high-resolution volume imaging of cleared testes
Moulzir M, Hazart D, Delhomme B, Oheim M, Ricard C : Reproduction, 2026 - Hyperspectral wavefront sensing with a multicore fiber
Baptiste Blochet, Nathalie Lebas, Pascal Berto, Dimitrios Papadopoulos, Marc Guillon : Nat Commun, 2026 - Projection-specific integration of convergent thalamic and retrosplenial signals in the presubicular head direction cortex.
Richevaux L, Lim D, Nassar M, Dias Rodrigues L, Mauthe C, Cohen I, Sol-Foulon N, Fricker D : Elife, 2025 - Divided attention and manual visuomotor control in stroke: a combined dual-task and eye movement study.
Dziezuk E, Le Boterff Q, Van Ravestyn C, Mairesse S, Hamdoun S, Calvet D, Daghsen L, Carment L, Rosso C, Maier MA, Turc G, Mas JL, G Lindberg P : J Neuroeng Rehabil, 2025 - Longitudinal brain ageing after stroke: a marker for neurodegeneration and its relevance for upper limb motor outcome.
Takyi RB, Plantin J, Charron S, Maier MA, Baron JC, Turc G, Rosso C, Debacker C, Lindberg PG : Brain Commun, 2025 - Decoding Wetting Behavior: Capillary Rise Experiments with Amphiphilic Compounds and Theoretical Aspects
Hamraoui A, Thuresson K, Nylander T : Langmuir, 2025 - Interfacing with the Brain: How Nanotechnology Can Contribute
Ahmed A A A, Alegret N, Almeida B, Alvarez-Puebla R, Andrews A M, Ballerini L, Barrios-Capuchino J J, Becker C, Blick R H, Bonakdar S, Chakraborty I, Chen X, Cheon J, Chilla G, Coelho Conceicao A L, Delehanty J, Dulle M, Efros A L, Epple M, Fedyk M, Feliu N, Feng M, Fernández-Chacón R, Fernandez-Cuesta I, Fertig N, Forster S, Garrido J A, George M, Guse A H, Hampp N, Harberts J, Han J, Heekeren H R, Hofmann U G, Holzapfel M, Hosseinkazemi H, Huang Y, Huber P, Hyeon T, Ingebrandt S, Ienca M, Iske A, Kang Y, Kasieczka G, Kim D-H, Kostarelos K, Lee J-H, Lin K-W, Liu S, Liu X, Liu Y, Lohr C, Mailänder V, Maffongelli L, Megahed S, Mews A, Mutas M, Nack L, Nakatsuka N, Oertner T G, Offenhäusser A, Oheim M, Otange B, Otto F, Patrono E, Peng B, Picchiotti A, Pierini F, Potter-Nerger M, Pozzi M, Pralle A, Prato M, Qi B, Ramos-Cabrer P, Genger U R, Ritter N, Rittner M, Roy S, Santoro F, Schuck N W, Schulz F, Şeker E, Skiba M, Sosniok M, Stephan H, Wang R, Wang T, Wegner K D, Weiss P S, Xu M, Yang C, Zargarian S S, Zeng Y, Zhou Y, Zhu D, Zierold R, Parak W J : ACS Nano, 2025 - BPS2025 - Human astrocyte calcium signaling in a cerebral organoid
Kaitlin Szederkenyi, Liliana Attisano, Martin Oheim, Christopher M Yip : Biophys J, 2025 - Rapid motor skill adjustment is associated with population-level modulation of cerebellar error signals.
Nguyen V, Gros C, Stell BM : Nat Neurosci, 2025 - The postsubiculum as a head-direction cortex.
Duszkiewicz AJ, Fricker D, Burgalossi A, Peyrache A : Trends Neurosci, 2025 - Spinal cord injury alters the therapeutic potential of olfactory ensheathing cells harvested in an autologous transplantation model
Delarue Q, Brodier M, Neveu P, Moncomble L, Raimond C, Robac A, Hugede A, Blondin A, Semprez F, Lecras P, Riou G, Guérout N : Stem Cell Res Ther, 2025 - Roles of lysosomal small-molecule transporters in metabolism and signaling.
Damme M, Guelle O, Löw C, Gasnier B : Trends Cell Biol, 2025 - Decoding wetting behavior: capillary rise experiments with amphiphilic compounds and theoretical aspects
Ahmed Hamraoui, Krister Thuresson, Tommy Nylander : Langmuir, 2025 - The alpha7 nicotinic acetylcholine receptor mediates network dysfunction in a mouse model of local amyloid pathology.
Koukouli F, Zhang CL, Lazarevich I, Rooy M, Lamotte d’Incamps B, Gaspar Santos D, Pons S, Peixoto J, Thiberge C, Nikolakopoulou I, Changeux JP, Bacci A, Gutkin BS, Schmidt-Hieber C, Maskos U : Mol Psychiatry, 2025 - Renshaw cells, corelease and nicotinic receptors: The last journey in synaptic transmission.
Lamotte d’Incamps B : Neuroscience, 2025 - Label-free, High-resolution Fluorescence Imaging of the Intestinal Wall by Image Scanning and Confocal Microscopy.
Moulzir M, Hazart D, Oheim M, Ricard C : Gastro Hep Adv, 2025 - Morphological heterogeneity of human astrocytes in cerebral organoids
Szederkenyi K, Au A, Attisano L, Oheim M, Yip C M : (preprint), 2025 - Involvement of the Endothelial N-Methyl-D-Aspartate Receptor on Vessel-Associated Positioning and Differentiation of Cortical Oligodendrocytes and on Motor Activity.
Beranger A, Lafenêtre M, Lacomme S, Lebon A, Genty D, Brosolo M, Janin F, Leroy A, Guérout N, Vivien D, Galas L, Marret S, Marguet F, Gontier E, Gonzalez BJ, Lecointre M : J Neurosci, 2025 - KCC2 enhancers normalize reflex responses and improve locomotor function after chronic spinal cord injury.
Bilchak JN, Danner SM, Caron G, Côté MP : J Physiol, 2025 - Beyond paralysis: Impact of spinal cord injury on brain inflammation and cognitive function through cell therapy.
Delarue Q, Guérout N : Neural Regen Res, 2025 - Cell adhesion and surface interactions: A comprehensive review of surface energy, wettability, and topography effects
Hamraoui A : AIP Advances, 2025 - Activation of Endogenous Spinal Cord Stem Cell Mediates Recovery Induced by Olfactory Ensheathing Cell Transplantation Following Spinal Cord Injury
Delarue Q, Honore A, Xu T, Chalfouh C, Di Giovanni M, Vaudry D, Li X, Guérout N : (preprint), 2025 - Modular Hydrogel-Based Nano-Bead Emitters for Bright, Homogeneous Fluorescent Thin Films and 3D Architectures
Ilya Olevsko, Maria Shahadeh, Eswaran Lakshmanan, Dmytro Ohorodniichuk, Eti Teblum, Moshe Feldberg, Leonid Weisman, Rotem Golan, Fabrice Licata, Martin Oheim, Gerardo Byk, Adi Salomon : Advanced Optical Materials, 2025 - Combinatorial Sample-and Back-Focal-Plane (BFP) Imaging. Pt. I: Instrument and acquisition parameters affecting BFP images and their analysis.
Shavit O, Suaudeau H, Julien C, Klimovsky H, Mañas-Chavernas N, Salomon A, Oheim M : Biophys J, 2025 - Bessel beams with an adjustable focal position
Zhalenchuck K, Bahabad A : Applied Optics, 2025 - Managing surface energy dynamics for enhanced axonal growth: An overview of present and future challenges
Sénépart O, Legay C, Hamraoui A : Biophysics Reviews, 2025 - Unveiling the Phenotypic Variability of Macrophages: Insights from Donor Diversity and Pooling Strategies.
Taciak B, Grochowska A, Górczak M, Górka E, Skorzynski M, Białasek M, Rygiel TP, Król M : Int J Mol Sci, 2025 - Harnessing macrophage-drug conjugates for allogeneic cell-based therapy of solid tumors via the TRAIN mechanism.
Taciak B, Bialasek M, Kubiak M, Marszalek I, Gorczak M, Osadchuk O, Kurpiel D, Strzemecki D, Barwik K, Skorzynski M, Nowakowska J, Lipiński W, Kiraga Ł, Brancewicz J, Klopfleisch R, Krzemiński Ł, Gorka E, Smolarska A, Padzinska-Pruszynska I, Siemińska M, Guzek J, Kutner J, Kisiala M, Wozniak K, Parisi G, Piacentini R, Cassetta L, Forrester LM, Bodnar L, Weiss T, Boffi A, Kucharzewska P, Rygiel TP, Krol M : Nat Commun, 2025 - A first morphological and electrophysiological characterization of Fañanas cells of the mouse cerebellum.
Singer A, Trigo F, Vinel L, Gruere O, Llano I, Oheim M : J Physiol, 2025 - Imaging the enteric nervous system
Doriane Hazart, Marwa Moulzir, Brigitte Delhomme, Martin Oheim, Clément Ricard : Front Neuroanat, 2025 - Fast tissue clearing and volume imaging techniques for anatomy
Clément Ricard, Doriane Hazart, Brigitte Delhomme, Marwa Moulzir, Irina Rakotoson, Martin Oheim : Microscopy Research & Technique (accepted), 2025 - Quantitative polarimetric wavefront imaging
Baptiste Blochet, Grégoire Lelu, Miguel A Alonso, Marc Guillon : Optica, 2025 - Complementary Speckle Stimulated Emission Depletion Microscopy
Payvand Arjmand, Samlan Chandran Thodika, Elsa Bivas, Haoyang Li, Martin Oheim, Hiroyuki Yoshida, Etienne Brasselet, Marc Guillon : ACS Photonics, 2025 - Ice templating water-stable macroporous polysaccharide hydrogels to mimic plant stems.
Komiyama K, Allard M, Eschenbrenner C, Sicard C, Hamraoui A, Fernandes F : Journal of Materials Chemistry B, 2025











