News
The SPPIN’s “Biophysics of the Brain” team wins the Claude Pompidou Prize for research into neurodegenerative disease
For its 13th edition, the Claude Pompidou Prize, worth €100,000, recognized the work of the “Biophysics of the Brain” team at the CNRS-SPPIN, Saints-Pères Paris Institute for the Neurosciences at Université Paris Cité, led by Martin Oheim. ...
Season 2025/26 of the Neural Networking Night seminar series (co-organized by SPPIN member)
We are excited to announce the new season of the Neural Networking Night seminar series! We look forward to welcoming you at Le Piano Vache for presentations by a fantastic line-up of neuroscientists from across Île-de-France. The new cycle will fea ...
Le SPPIN rencontre l’art en septembre !
L’équipe 8 “Orientation & Coordination » organise un événement de médiation scientifique autour des Neurosciences, le 22-28 Septembre 2025, à la Capitainerie de l’Isle, 26 rue Chanoinesse, 75004 Paris. Plongez dans l’univers f ...
EMBO SHORT TERM FELLOW Keren Zahlenchuck joins the SPPIN to work on advanced beam shaping strategies for mesoscale light-sheet microscopy
Keren Zahlenchuck is going to rejoin SPPIN’s team “Biophysics of the brain” (Oheim, https://www.sppin.fr/) from 1 September onwards. Keren is the recipient of an EMBO short term fellowship and will be working with Brieuc Chauvin, Hugo Touja ...
10 June 2025 – Stephanie RUDOLPH – A Mechanism for Amplifying Sparse Neuromodulatory Signals in Electrically Coupled Interneuron Networks
Prof Stephanie RUDOLPH, Albert Einstein College of Medicine, New York SPPIN’s webinar 2025, 10 June at 11h, SPPIN common room, 3rd floor A Mechanism for Amplifying Sparse Neuromodulatory Signals in Electrically Coupled Interneuron Networks ...
20 Mai 2025 – Alexandra FRAGOLA – Fast adaptive optics light-sheet microscopy for in vivo high-resolution imaging at depth
Prof Alexandra FRAGOLA, ISMO, Université Paris Saclay (Orsay) SPPIN’s webinar 2024, 20 May at 11h, SPPIN common room, 3rd floor Fast adaptive optics light-sheet microscopy for in vivo high-resolution imaging at depth The study of fast biolo ...
The Association Française du Syndrome de Rett supports Nicolas PANAYOTIS
Congratulations to Nicolas PANAYOTIS (Team 7) who was awarded a 3-years Research Grant by the French Rett Syndrome Patient Advocacy Organization “Association Française du Syndrome de Rett” (or AFSR). Funded project: NewMOTORS ‘Development ...
SPPIN’s Floriane Eshak receives distinguished thesis award for advancing psychiatric treatment
Floriane Eshak, who conducted her doctoral research at SPPIN laboratory last year, has been awarded a prestigious 2024 Solemn Thesis Prize from the Chancellerie des universités de Paris. Under the supervision of Francine Acher (SPPIN team 6) and Anne Gou ...
Brandon Stell and Boris Barbour’s PubPeer Wins the 200.000€’s Einstein Award
The Einstein Foundation has awarded its prestigious 2024 Institutional Award to PubPeer, the post-publication peer review platform co-founded by SPPIN’s Brandon Stell and IBENS’s Boris Barbour. The foundation award, in collaboration with th ...
2 Open PhD and 14 Master projects
SPPIN is recruiting ! 14 open Master projects Here are the titles : Team 1 – Biophysics of the brain : Imaging the dissipation of Ca2+ micro domains w/ SAF BFP imaging A reproducible metric for tissue clearing with quantitative phase ...
Next seminars
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Fresh from the press
Articles
- Rapid Motor Adaptation via Population-level Modulation of Cerebellar Error Signals
Vinh Nguyen, Brandon M Stell : (preprint), in press - Associative plasticity of granule cell inputs to cerebellar Purkinje cells
Rossella Conti, Céline Auger : (preprint), in press - KCC2 enhancers normalize reflex responses and improve locomotor function after chronic spinal cord injury.
Bilchak JN, Danner SM, Caron G, Côté MP : J Physiol, 2025 - Beyond paralysis: Impact of spinal cord injury on brain inflammation and cognitive function through cell therapy.
Delarue Q, Guérout N : Neural Regen Res, 2025 - Cell adhesion and surface interactions: A comprehensive review of surface energy, wettability, and topography effects
Hamraoui A : AIP Advances, 2025 - Activation of Endogenous Spinal Cord Stem Cell Mediates Recovery Induced by Olfactory Ensheathing Cell Transplantation Following Spinal Cord Injury
Delarue Q, Honore A, Xu T, Chalfouh C, Di Giovanni M, Vaudry D, Li X, Guérout N : (preprint), 2025 - Modular Hydrogel-Based Nano-Bead Emitters for Bright, Homogeneous Fluorescent Thin Films and 3D Architectures
Ilya Olevsko, Maria Shahadeh, Eswaran Lakshmanan, Dmytro Ohorodniichuk, Eti Teblum, Moshe Feldberg, Leonid Weisman, Rotem Golan, Fabrice Licata, Martin Oheim, Gerardo Byk, Adi Salomon : Advanced Optical Materials, 2025 - Combinatorial Sample-and Back-Focal-Plane (BFP) Imaging. Pt. I: Instrument and acquisition parameters affecting BFP images and their analysis.
Shavit O, Suaudeau H, Julien C, Klimovsky H, Mañas-Chavernas N, Salomon A, Oheim M : Biophys J, 2025 - Bessel beams with an adjustable focal position
Zhalenchuck K, Bahabad A : Applied Optics, 2025 - Managing surface energy dynamics for enhanced axonal growth: An overview of present and future challenges
Sénépart O, Legay C, Hamraoui A : Biophysics Reviews, 2025 - Unveiling the Phenotypic Variability of Macrophages: Insights from Donor Diversity and Pooling Strategies.
Taciak B, Grochowska A, Górczak M, Górka E, Skorzynski M, Białasek M, Rygiel TP, Król M : Int J Mol Sci, 2025 - Harnessing macrophage-drug conjugates for allogeneic cell-based therapy of solid tumors via the TRAIN mechanism.
Taciak B, Bialasek M, Kubiak M, Marszalek I, Gorczak M, Osadchuk O, Kurpiel D, Strzemecki D, Barwik K, Skorzynski M, Nowakowska J, Lipiński W, Kiraga Ł, Brancewicz J, Klopfleisch R, Krzemiński Ł, Gorka E, Smolarska A, Padzinska-Pruszynska I, Siemińska M, Guzek J, Kutner J, Kisiala M, Wozniak K, Parisi G, Piacentini R, Cassetta L, Forrester LM, Bodnar L, Weiss T, Boffi A, Kucharzewska P, Rygiel TP, Krol M : Nat Commun, 2025 - A first morphological and electrophysiological characterization of Fañanas cells of the mouse cerebellum.
Singer A, Trigo F, Vinel L, Gruere O, Llano I, Oheim M : J Physiol, 2025 - Imaging the enteric nervous system
Doriane Hazart, Marwa Moulzir, Brigitte Delhomme, Martin Oheim, Clément Ricard : Front Neuroanat, 2025 - Fast tissue clearing and volume imaging techniques for anatomy
Clément Ricard, Doriane Hazart, Brigitte Delhomme, Marwa Moulzir, Irina Rakotoson, Martin Oheim : Microscopy Research & Technique (accepted), 2025 - Complementary Speckle Stimulated Emission Depletion Microscopy
Payvand Arjmand, Samlan Chandran Thodika, Elsa Bivas, Haoyang Li, Martin Oheim, Hiroyuki Yoshida, Etienne Brasselet, Marc Guillon : ACS Photonics, 2025 - Ice templating water-stable macroporous polysaccharide hydrogels to mimic plant stems.
Komiyama K, Allard M, Eschenbrenner C, Sicard C, Hamraoui A, Fernandes F : Journal of Materials Chemistry B, 2025 - Acoustic levitation as a tool for cell-driven self-organization of human cell spheroids during long-term 3D culture.
Rabiet L, Arakelian L, Jeger-Madiot N, García DR, Larghero J, Aider JL : Biotechnol Bioeng, 2024 - Improved functionality of hepatic spheroids cultured in acoustic levitation compared to existing 2D and 3D models
Lucile Rabiet, Nathan Jeger-Madiot, Duván Rojas García, Lucie Tosca, Gérard Tachdjian, Sabrina Kellouche, Rémy Agniel, Jérôme Larghero, Jean-Luc Aider, Lousineh Arakelian : Sci Rep, 2024 - Breast Cancer Plasticity after Chemotherapy Highlights the Need for Re-Evaluation of Subtyping in Residual Cancer and Metastatic Tissues.
Padzińska-Pruszyńska IB, Akbar MW, Isbilen M, Górka E, Kucukkaraduman B, Canlı SD, Dedeoğlu E, Azizolli S, Cela I, Akcay AG, Hakanoglu H, Bodnar L, Cierniak S, Kozielec Z, Pruszyński JJ, Bittel M, Gure AO, Król M, Taciak B : Int J Mol Sci, 2024 - The Molecules Lost New Compounds Binding at the Histamine Site of the NMDA Receptor (NMDA(HA)R).
Armand V : Adv Neur Neur Sci, 2024 - Histamine H1-receptor-mediated modulation of NMDA receptors signaling responses
J-M Arrang, V Armand : Pharmacol Res Perspect, 2024 - Brain inflammation and cognitive decline induced by spinal cord injury can be reversed by spinal cord cell transplants
Q Delarue, A Robac, F Semprez, C Duclos, B Pileyre, P Neveu, C Raimond, G Riou, I Ziane, N Guérout : Brain Behav Immun, 2024 - Spinal microcircuits go through multiphasic homeostatic compensations in a mouse model of motoneuron degeneration.
Nascimento F, Özyurt MG, Halablab K, Bhumbra GS, Caron G, Bączyk M, Zytnicki D, Manuel M, Roselli F, Brownstone R, Beato M : Cell Rep, 2024 - Contributions of Surface and Interface Physical Chemistry to Biology
Ahmed Hamraoui : (preprint), 2024 - Hyperspectral wavefront sensing with a multicore fiber
Baptiste Blochet, Nathalie Lebas, Pascal Berto, Dimitrios Papadopoulos, Marc Guillon : (under review at Nat Commun), 2024 - A Polarimetric Wavefront Imager
Baptiste Blochet, Grégoire Lelu, Miguel A Alonso, Marc Guillon : (under review at Optica), 2024 - Projection-specific integration of convergent thalamic and retrosplenial signals in the presubicular head direction cortex
Louis Richevaux, Dongkyun Lim, Mérie Nassar, Léa Dias Rodrigues, Constanze Mauthe, Ivan Cohen, Nathalie Sol-Foulon, Desdemona Fricker : (preprint), 2024 - Presubicular VIP expressing interneurons receive facilitating excitation from anterior thalamus.
Nassar M, Richevaux L, Lim D, Tayupo D, Martin E, Fricker D : Neuroscience, 2024 - Involvement of kinases in memory consolidation of inhibitory avoidance training.
Montiel I, Bello-Medina PC, Prado-Alcalá RA, Quirarte GL, Verdín-Ruvalcaba LA, Marín-Juárez TA, Medina AC : Rev Neurosci, 2024 - Elucidating the Activation Mechanism of the Proton-sensing GPR68 Receptor.
Matsingos C, Howell LA, McCormick PJ, Fornili A : J Mol Biol, 2024 - The gut, a whistleblower, in the early stages of Parkinson’s disease
Doriane Hazart, Malvyne Rolli-Derkinderen, Brigitte Delhomme, Pascal Derkinderen, Martin Oheim, Clément Ricard : Médecine/sciences, 2024 - Characterizing human astrocyte calcium signaling in a cerebral organoid
Kaitlin Szederkenyi, Liliana Attisano, Martin Oheim, Christopher M Yip : Biophys J, 2024 - L’intestin, lanceur d’alerte, dans les prémices de la maladie de Parkinson
Doriane Hazart, Malvyne Rolli-Derkinderen, Brigitte Delhomme, Pascal Derkinderen, Martin Oheim, Clément Ricard : Médecine/sciences, 2024 - Lesion-induced impairment of therapeutic capacities of olfactory ensheathing cells in an autologous transplantation model for treatment of spinal cord injury
Quentin Delarue, Matthis Brodier, Pauline Neveu, Laurine Moncomble, Alizée Hugede, Axelle Blondin, Amandine Robac, Clémence Raimond, Pamela Lecras, Gaëtan Riou, Nicolas Guérout : (preprint), 2024 - Complementarity between Brillouin signature and Scholte wave for controlled elasticity in fibrillated collagen medium for culture cell
Ahmed Hamraoui, Océane Sénépart, Laurent Belliard : Applied Physics Letters, 2024 - MFSD1 with its accessory subunit GLMP functions as a general dipeptide uniporter in lysosomes
Katharina Esther Julia Jungnickel, Océane Guelle, Miharu Iguchi, Wentao Dong, Vadim Kotov, Florian Gabriel, Cécile Debacker, Julien Dairou, Isabelle McCort-Tranchepain, Nouf N Laqtom, Sze Ham Chan, Akika Ejima, Kenji Sato, David Massa López, Paul Saftig, Ahmad Reza Mehdipour, Monther Abu-Remaileh, Bruno Gasnier, Christian Löw, Markus Damm : Nature Cell Biology, 2024 - Novel Inhibitory Site Revealed by XAP044 Mode of Action on the Metabotropic Glutamate 7 Receptor Venus Flytrap Domain.
Cristiano N, Cabayé A, Brabet I, Glatthar R, Tora A, Goudet C, Bertrand HO, Goupil-Lamy A, Flor PJ, Pin JP, McCort-Tranchepain I, Acher FC : J Med Chem, 2024 - Epitope Identification of an mGlu5 Receptor Nanobody Using Physics-Based Molecular Modeling and Deep Learning Techniques.
Eshak F, Pion L, Scholler P, Nevoltris D, Chames P, Rondard P, Pin JP, Acher FC, Goupil-Lamy A : J Chem Inf Model, 2024 - CBX3 antagonizes IFNγ/STAT1/PD-L1 axis to modulate colon inflammation and CRC chemosensitivity.
Xiang Y, Mata-Garrido J, Fu Y, Desterke C, Batsché E, Hamaï A, Sedlik C, Sereme Y, Skurnik D, Jalil A, Onifarasoaniaina R, Frapy E, Beche JC, Alao R, Piaggio E, Arbibe L, Chang Y : EMBO Mol Med, 2024 - Single-shot digital optical fluorescence phase conjugation through forward multiple-scattering samples
TENGFEI WU, YIXUAN ZHANG, BAPTISTE BLOCHET, PAYVAND ARJMAND, PASCAL BERTO, AND MARC GUILLON : Science advances, 2024 - Multiplexed wavefront sensing with a thin diffuser
Tengfei Wu, Marc Guillon, Gilles Tessier, and Pascal Berto : Optica, 2024 - Design, Synthesis, Pharmacology, and In Silico Studies of (1S,2S,3S)-2-((S)-Amino(carboxy)methyl)-3-(carboxymethyl)cyclopropane-1-carboxylic Acid (LBG30300): A Picomolar Potency Subtype-Selective mGlu(2) Receptor Agonist.
Liu N, Eshak F, Malhaire F, Brabet I, Prézeau L, Renard E, Pin JP, Acher FC, Staudt M, Bunch L : J Med Chem, 2024 - A maximum of two readily releasable vesicles per docking site at a cerebellar single active zone synapse.
Silva M, Tran V, Marty A : Elife, 2024 - A colour-encoded nanometric ruler for axial super-resolution microscopies
Ilya Olevsko, Omer Shavit, Moshe Feldberg, Yossi Abulafia, Adi Salomon, Martin Oheim : Optics Communications, 2024