
SPPIN - Saints-Pères Paris Institute for the Neurosciences - CNRS UMR 8003
Université Paris Cité
F-75006 Paris
France
Dr. Philippe Djian
Senior Research Scientist, CNRS
Team 1 - Biophysics of the brain
philippe.djian@-Code to remove to avoid SPAM-u-paris.fr
+33 1 76 53 42 10
Recent Publications
Articles
- Fast 3-D Imaging of Brain Organoids With a New Single-Objective Planar-Illumination Two-Photon Microscope.
Rakotoson I, Delhomme B, Djian P, Deeg A, Brunstein M, Seebacher C, Uhl R, Ricard C, Oheim M : Front Neuroanat, 2019 - Fast 3-D Imaging of Brain Organoids With a New Single-Objective Planar-Illumination Two-Photon Microscope
Irina Rakotoson, Brigitte Delhomme, Philippe Djian, Andreas Deeg, Maia Brunstein, Christian Seebacher, Rainer Uhl, Clement Ricard, Martin Oheim : Front Neuroanat, 2019 - The importance of basonuclin 2 in adult mice and its relation to basonuclin 1.
Vanhoutteghem A, Delhomme B, Hervé F, Nondier I, Petit JM, Araki M, Araki K, Djian P : Mech Dev, 2016 - The zinc-finger protein basonuclin 2 is required for proper mitotic arrest, prevention of premature meiotic initiation and meiotic progression in mouse male germ cells.
Vanhoutteghem A, Messiaen S, Hervé F, Delhomme B, Moison D, Petit JM, Rouiller-Fabre V, Livera G, Djian P : Development, 2014 - Synchrotron-based infrared spectroscopy brings to light the structure of protein aggregates in neurodegenerative diseases
Hoffner G, André W, Sandt C, Djian P : Reviews in Analytical Chemistry, 2014 - Monomeric, oligomeric and polymeric proteins in huntington disease and other diseases of polyglutamine expansion.
Hoffner G, Djian P : Brain Sci, 2014 - Polyglutamine Aggregation in Huntington Disease: Does Structure Determine Toxicity?
Hoffner G, Djian P : Mol Neurobiol, 2014 - Structure of inclusions of Huntington\\’s disease brain revealed by synchrotron infrared microspectroscopy: polymorphism and relevance to cytotoxicity.
André W, Sandt C, Dumas P, Djian P, Hoffner G : Anal Chem, 2013 - Human balanced translocation and mouse gene inactivation implicate Basonuclin 2 in distal urethral development.
Bhoj EJ, Ramos P, Baker LA, Garg V, Cost N, Nordenskjöld A, Elder FF, Bleyl SB, Bowles NE, Arrington CB, Delhomme B, Vanhoutteghem A, Djian P, Zinn AR : Eur J Hum Genet, 2011 - Transglutaminase in epidermis and neurological disease or what makes a good cross-linking substrate.
Hoffner G, Vanhoutteghem A, André W, Djian P : Adv Enzymol Relat Areas Mol Biol, 2011 - Human balanced translocation and mouse gene inactivation implicate Basonuclin 2 in distal urethral development.
Bhoj EJ, Ramos P, Baker LA, Cost N, Nordenskjöld A, Elder FF, Bleyl SB, Bowles NE, Arrington CB, Delhomme B, Vanhoutteghem A, Djian P, Zinn AR : Eur J Hum Genet, 2011 - Transglutaminase-catalyzed crosslinking in neurological disease: from experimental evidence to therapeutic inhibition.
Hoffner G, André W, Vanhoutteghem A, Souès S, Djian P : CNS Neurol Disord Drug Targets, 2010 - Basonuclin 2 has a function in the multiplication of embryonic craniofacial mesenchymal cells and is orthologous to disco proteins.
Vanhoutteghem A, Maciejewski-Duval A, Bouche C, Delhomme B, Hervé F, Daubigney F, Soubigou G, Araki M, Araki K, Yamamura K, Djian P : Proc Natl Acad Sci U S A, 2009 - Basonuclin 2 has a function in the multiplication of embryonic craniofacial mesenchymal cells and is orthologous to disco proteins.
Vanhoutteghem A, Maciejewski-Duval A, Bouche C, Delhomme B, Hervé F, Daubigney F, Soubigou G, Araki M, Araki K, Yamamura K, Djian P : Proc Natl Acad Sci U S A, 2009 - [Nepsilon-(gamma-glutamyl) lysine] as a potential biomarker in neurological diseases: new detection method and fragmentation pathways.
Hoffner G, Hoppilliard Y, van der Rest G, Dansette P, Djian P, Ohanessian G : J Mass Spectrom, 2008 - Misfolding of proteins with a polyglutamine expansion is facilitated by proteasomal chaperones.
Rousseau E, Kojima R, Hoffner G, Djian P, Bertolotti A : J Biol Chem, 2008 - Aggregation of expanded huntingtin in the brains of patients with Huntington disease.
Hoffner G, Souès S, Djian P : Prion, 2007 - Systematic repeat addition at a precise location in the coding region of the involucrin gene of wild mice reveals their phylogeny.
Djian P, Delhomme B : Genetics, 2005 - Transglutaminase and diseases of the central nervous system.
Hoffner G, Djian P : Front Biosci, 2005 - Purification of neuronal inclusions of patients with Huntington\\’s disease reveals a broad range of N-terminal fragments of expanded huntingtin and insoluble polymers.
Hoffner G, Island ML, Djian P : J Neurochem, 2005 - Oligomeric and polymeric aggregates formed by proteins containing expanded polyglutamine.
Iuchi S, Hoffner G, Verbeke P, Djian P, Green H : Proc Natl Acad Sci U S A, 2003 - Perinuclear localization of huntingtin as a consequence of its binding to microtubules through an interaction with beta-tubulin: relevance to Huntington\\’s disease.
Hoffner G, Kahlem P, Djian P : J Cell Sci, 2002 - Protein aggregation in Huntington\\’s disease.
Hoffner G, Djian P : Biochimie, 2002 - Expansion of mouse involucrin by intra-allelic repeat addition.
Delhomme B, Djian P : Gene, 2000 - Origin of the polymorphism of the involucrin gene in Asians.
Djian P, Delhomme B, Green H : Am J Hum Genet, 1995