Team 2 – Cerebellar Neurophysiology
The members of the Cerebellar Physiology team are working together to unravel the role of the cerebellum in sensorimotor integration, from synaptic to systems levels. We use our strong interest in neurophysiology and development of optical tools for neuroscience to explore the biophysics of synaptic transmission and how it is integrated by the cerebellar cortex microcircuit during sensorimotor integration in awake behaving animals. Our team combines complementary technical expertise in cerebellar physiology ranging from single synapse electrophysiology up to imaging populations of neurons in mice performing cerebellar-dependent motor tasks.
Team leaders
Céline Auger, Research Scientist, CNRS, Team 2 - Cerebellar Neurophysiology, +33 1 76 53 43 41 (switchboard)
Brandon Stell, Research Scientist, CNRS, Team 2 - Cerebellar Neurophysiology, +33 1 76 53 43 41 (switchboard)
Members
Muriel Amar, Assistant Professor, Team 2 - Cerebellar Neurophysiology, +33 1 76 53 43 41 (switchboard)
Thibault Collin, Professor, PI, Paris Diderot, Team 2 - Cerebellar Neurophysiology, +33 1 76 53 43 41 (switchboard)
Isabel Llano, Senior Research Scientist Emeritus, CNRS, Team 2 - Cerebellar Neurophysiology, +33 1 76 53 43 41 (switchboard)
Alain Marty, Senior Research Scientist Emeritus, CNRS, Team 2 - Cerebellar Neurophysiology, +33 1 76 53 43 41 (switchboard)
Melissa Silva-Medina Weil, Postdoctoral Researcher, Team 2 - Cerebellar Neurophysiology, +33 1 76 53 43 41 (switchboard)
Recent Publications
Articles
- Rapid Motor Adaptation via Population-level Modulation of Cerebellar Error Signals
Vinh Nguyen, Brandon M Stell : (preprint), in press - Associative plasticity of granule cell inputs to cerebellar Purkinje cells
Rossella Conti, Céline Auger : (preprint), in press - Rapid motor skill adjustment is associated with population-level modulation of cerebellar error signals.
Nguyen V, Gros C, Stell BM : Nat Neurosci, 2025 - A first morphological and electrophysiological characterization of Fañanas cells of the mouse cerebellum.
Singer A, Trigo F, Vinel L, Gruere O, Llano I, Oheim M : J Physiol, 2025 - A maximum of two readily releasable vesicles per docking site at a cerebellar single active zone synapse.
Silva M, Tran V, Marty A : Elife, 2024 - Depolarization-induced bursts of miniature synaptic currents in individual synapses of developing cerebellum.
Le Guellec B, Gomez LC, Malagon G, Collin T, Marty A : J Gen Physiol, 2023 - Prioritized docking of synaptic vesicles provided by a rapid recycling pathway
Tran V, Silva M, Marty A : IScience, 2023 - KCa1.1 channels contribute to optogenetically driven post-stimulation silencing in cerebellar molecular layer interneurons.
Kassa M, Bradley J, Jalil A, Llano I : J Gen Physiol, 2023 - The cell polarity protein Vangl2 in the muscle shapes the neuromuscular synapse by binding to and regulating the tyrosine kinase MuSK.
Boëx M, Cottin S, Halliez M, Bauché S, Buon C, Sans N, Montcouquiol M, Molgó J, Amar M, Ferry A, Lemaitre M, Rouche A, Langui D, Baskaran A, Fontaine B, Messéant J, Strochlic L : Sci Signal, 2022 - Calcium-dependent docking of synaptic vesicles.
Silva M, Tran V, Marty A : Trends Neurosci, 2021