6 jully 2026 – Alexander ROHRBACH – ROCS – Label free imaging and 160 nm spatial and 10 ms temporal resolution

Prof Alexander ROHRBACH – Bio- and Nano-Photonics research group, IMTEC, University of Freiburg, Germany

SPPIN’s seminar series spring-summer 2026, 6 jully 2026 11h00, SPPIN common room, 3rd floor, E368

ROCS – Label free imaging and 160 nm spatial and 10 ms temporal resolution

Rotating coherent scattering (ROCS) microscopy is a label-free optical imaging technique developed in our lab. It is based on coherent elastic backscattering of an obliquely incident, collimated laser beam that rotates azimuthally around the optical axis. The method can be used to image both biological cells and sub-wavelength particles. Under highly oblique illumination, the achievable spatial resolution approaches nearly twice that obtained with conventional normal illumination. During the rotation within the camera exposure time, intensity images corresponding to different illumination directions are integrated by the camera. Due to significantly lower laser powers menus in fluorescence microscopy, is excellently suited for live cell imaging. I will present and discuss basic concepts of coherent and incoherent superresolution imaging as well as recent results about binding of virus-like particles to cells and enabling material specificity in ROCS.

Please contact Martin Oheim if you want to make an appointment with Anne Sentenac