
SPPIN - Saints-Pères Paris Institute for the Neurosciences - CNRS UMR 8003
Université Paris Cité
F-75006 Paris
France
Dr. Claire Desnos
Research Scientist, CNRS
Team 4 - Membrane dynamics
claire.desnos@-Code to remove to avoid SPAM-u-paris.fr
+33 1 70 64 99 19, room 626
Recent Publications
Articles
- A role for BDNF- and NMDAR-induced lysosomal recruitment of mTORC1 in the regulation of neuronal mTORC1 activity.
Khamsing D, Lebrun S, Fanget I, Larochette N, Tourain C, de Sars V, Brunstein M, Oheim M, Carrel D, Darchen F, Desnos C : Mol Brain, 2021 - Increased signaling by the autism-related Engrailed-2 protein enhances dendritic branching and spine density, alters synaptic structural matching, and exaggerates protein synthesis.
Soltani A, Lebrun S, Carpentier G, Zunino G, Chantepie S, Maïza A, Bozzi Y, Desnos C, Darchen F, Stettler O : PLOS ONE, 2017 - Meeting after meeting: 20 years of discoveries by the members of the Exocytosis-Endocytosis Club.
Niedergang F, Gasman S, Vitale N, Desnos C, Lamaze C : Biol Cell, 2017 - Increased signaling by the autism-related Engrailed-2 protein enhances dendritic branching and spine density, alters synaptic structural matching, and exaggerates protein synthesis.
Soltani A, Lebrun S, Carpentier G, Zunino G, Chantepie S, Maïza A, Bozzi Y, Desnos C, Darchen F, Stettler O : PLoS One, 2017 - Superresolving dendritic spine morphology with STED microscopy under holographic photostimulation.
Lauterbach MA, Guillon M, Desnos C, Khamsing D, Jaffal Z, Darchen F, Emiliani V : Neurophotonics, 2016 - Polarity protein Par3 controls B-cell receptor dynamics and antigen extraction at the immune synapse.
Reversat A, Yuseff MI, Lankar D, Malbec O, Obino D, Maurin M, Penmatcha NV, Amoroso A, Sengmanivong L, Gundersen GG, Mellman I, Darchen F, Desnos C, Pierobon P, Lennon-Duménil AM : Mol Biol Cell, 2015 - Cdc42 controls the dilation of the exocytotic fusion pore by regulating membrane tension.
Bretou M, Jouannot O, Fanget I, Pierobon P, Larochette N, Gestraud P, Guillon M, Emiliani V, Gasman S, Desnos C, Lennon-Duménil AM, Darchen F : Mol Biol Cell, 2014 - Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia.
Monteiro P, Rossé C, Castro-Castro A, Irondelle M, Lagoutte E, Paul-Gilloteaux P, Desnos C, Formstecher E, Darchen F, Perrais D, Gautreau A, Hertzog M, Chavrier P : J Cell Biol, 2013 - Myrip couples the capture of secretory granules by the actin-rich cell cortex and their attachment to the plasma membrane.
Huet S, Fanget I, Jouannot O, Meireles P, Zeiske T, Larochette N, Darchen F, Desnos C : J Neurosci, 2012 - Polarized Secretion of Lysosomes at the B Cell Synapse couples Antigen Extraction to Processing and Presentation
Yuseff MI, Reversat A, Lankar D, Diaz J, Fanget I, Pierobon P, Randrian V, Larochette N, Vascotto F, Desdouets C, Jauffred B, Bellaiche Y, Gasman S, Darchen F, Desnos C, Lennon-Duménil AM : Immunity, 2011 - Rab27a and Rab27b control different steps of the exosome secretion pathway.
Ostrowski M, Carmo NB, Krumeich S, Fanget I, Raposo G, Savina A, Moita CF, Schauer K, Hume AN, Freitas RP, Goud B, Benaroch P, Hacohen N, Fukuda M, Desnos C, Seabra MC, Darchen F, Amigorena S, Moita LF, Thery C : Nat Cell Biol, 2010 - \\’Should I stay or should I go?\\’: myosin V function in organelle trafficking.
Desnos C, Huet S, Darchen F : Biol Cell, 2007 - Myosin va mediates docking of secretory granules at the plasma membrane.
Desnos C, Huet S, Fanget I, Chapuis C, Böttiger C, Racine V, Sibarita JB, Henry JP, Darchen F : J Neurosci, 2007 - Serotonin secretion by human carcinoid BON cells.
Tran VS, Marion-Audibert AM, Karatekin E, Huet S, Cribier S, Guillaumie K, Chapuis C, Desnos C, Darchen F, Henry JP : Ann N Y Acad Sci, 2004 - Transmitter uptake and release in PC12 cells overexpressing plasma membrane monoamine transporters.
Schonn JS, Desnos C, Henry JP, Darchen F : J Neurochem, 2003 - Rab27A and its effector MyRIP link secretory granules to F-actin and control their motion towards release sites.
Desnos C, Schonn JS, Huet S, Tran VS, El-Amraoui A, Raposo G, Fanget I, Chapuis C, Ménasché G, de Saint Basile G, Petit C, Cribier S, Henry JP, Darchen F : J Cell Biol, 2003 - MyRIP, a novel Rab effector, enables myosin VIIa recruitment to retinal melanosomes.
El-Amraoui A, Schonn JS, Küssel-Andermann P, Blanchard S, Desnos C, Henry JP, Wolfrum U, Darchen F, Petit C : EMBO Rep, 2002 - Which step of exocytosis is regulated by the monomeric GTPase Rab3a?
Schonn JS, Desnos C, Darchen F, Henry JP : Ann N Y Acad Sci, 2002 - Vesiculation and sorting from PC12-derived endosomes in vitro.
Lichtenstein Y, Desnos C, Faúndez V, Kelly RB, Clift-O\\’Grady L : Proc Natl Acad Sci U S A, 1998 - Reconstitution of synaptic vesicle biogenesis from PC12 cell membranes.
Clift-O\\’Grady L, Desnos C, Lichtenstein Y, Faúndez V, Horng JT, Kelly RB : Methods, 1998 - Long term stimulation changes the vesicular monoamine transporter content of chromaffin granules.
Desnos C, Laran MP, Langley K, Aunis D, Henry JP : J Biol Chem, 1995 - Biogenesis of synaptic vesicles in vitro.
Desnos C, Clift-O\\’Grady L, Kelly RB : J Cell Biol, 1995 - Biochemistry and molecular biology of the vesicular monoamine transporter from chromaffin granules.
Henry JP, Botton D, Sagne C, Isambert MF, Desnos C, Blanchard V, Raisman-Vozari R, Krejci E, Massoulie J, Gasnier B : J Exp Biol, 1994 - The catecholamine transporter of adrenal medulla chromaffin granules.
Henry JP, Gasnier B, Desnos C, Scherman D, Krejci E, Massoulié J : Ann N Y Acad Sci, 1994
Chapter
- Masterclass with Rab3 and Rab27: orchestring secretion (PDF)
Darchen F, Desnos C : extracted from Rab GTPases and membrane trafficking Guangpu Li, Nava Segev - Ben tham Science Publishers, pages 55-76, ISBN:978-1-60805-391-9, 2012